Anti-BTNL2 Antibody (CAB14142)
- SKU:
- CAB14142
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-BTNL2 Antibody |
抗体コード: | CAB14142 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LKVN GPSQ PILV RVGE DIQL TCYL SPKA NAQS MEVR WDRS HRYP AVHV YMDG DHVA GEQM AEYR GRTV LVSD AIDE GRLT LQIL SARP SDDG QYRC LFEK DDVY QEAS LDLK VVSL GSSP LITV EGQE DGEM QPMC SSDG WFPQ PHVP WRDM EGKT IPSS SQAL TQGS HGLF HVQT LLRV TNIS AVDV TCSI SIPF LGEE KIAT FSLS GW |
遺伝子ID: | 56244 |
Uniprot: | Q9UIR0 |
セルラーロケーション: | Membrane, Single-pass type II membrane protein |
計算された分子量: | 19kDa/27kDa/28kDa/30kDa/43kDa/50kDa |
観察された分子量: | Refer to figures |
同義語: | BTNL2, BTL-II, BTN7, HSBLMHC1, SS2 |
バックグラウンド: | This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. |
NCBI Summary: | This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. [provided by RefSeq, May 2017] |
UniProt Code: | Q9UIR0 |
NCBI GenInfo Identifier: | 73921189 |
NCBI Gene ID: | 56244 |
NCBI Accession: | Q9UIR0.1 |
UniProt Related Accession: | Q9UIR0 |
Molecular Weight: | 19kDa; 27kDa; 28kDa; 30kDa; 43kDa; 50kDa |
NCBI Full Name: | Butyrophilin-like protein 2 |
NCBI Synonym Full Names: | butyrophilin like 2 |
NCBI Official Symbol: | BTNL2 |
NCBI Official Synonym Symbols: | SS2; BTN7; BTL-II; HSBLMHC1 |
NCBI Protein Information: | butyrophilin-like protein 2 |
UniProt Protein Name: | Butyrophilin-like protein 2 |
Protein Family: | Butyrophilin-like protein |
UniProt Gene Name: | BTNL2 |
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