Anti-BTG1 Antibody (CAB6359)
- SKU:
- CAB6359
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-BTG1 Antibody |
| 抗体コード: | CAB6359 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-171 of human BTG1 (NP_001722.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-171 of human BTG1 (NP_001722.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ISKF LRTK GLTS ERQL QTFS QSLQ ELLA EHYK HHWF PEKP CKGS GYRC IRIN HKMD PLIG QAAQ RIGL SSQE LFRL LPSE LTLW VDPY EVSY RIGE DGSI CVLY EASP AGGS TQNS TNVQ MVDS RISC KEEL LLGR TSPS KNYN MMTV SG |
| 遺伝子ID: | 694 |
| Uniprot: | P62324 |
| セルラーロケーション: | |
| 計算された分子量: | 19kDa |
| 観察された分子量: | Refer to Figures |
| 同義語: | BTG1, APRO2 |
| バックグラウンド: | This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. |
| UniProt Protein Function: | BTG1: Anti-proliferative protein. A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC. Belongs to the BTG family. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Oncoprotein Chromosomal Location of Human Ortholog: 12q22 Cellular Component: cytoplasm; nucleus Molecular Function:enzyme binding; protein binding Biological Process: negative regulation of cell proliferation; positive regulation of angiogenesis; positive regulation of endothelial cell differentiation; positive regulation of myoblast differentiation |
| NCBI Summary: | This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008] |
| UniProt Code: | P62324 |
| NCBI GenInfo Identifier: | 59799172 |
| NCBI Gene ID: | 694 |
| NCBI Accession: | P62324.1 |
| UniProt Secondary Accession: | P62324,P31607, |
| UniProt Related Accession: | P62324 |
| Molecular Weight: | 19,209 Da |
| NCBI Full Name: | Protein BTG1 |
| NCBI Synonym Full Names: | BTG anti-proliferation factor 1 |
| NCBI Official Symbol: | BTG1 |
| NCBI Official Synonym Symbols: | APRO2 |
| NCBI Protein Information: | protein BTG1 |
| UniProt Protein Name: | Protein BTG1 |
| UniProt Synonym Protein Names: | B-cell translocation gene 1 protein |
| Protein Family: | Protein |
| UniProt Gene Name: | BTG1 |
| UniProt Entry Name: | BTG1_HUMAN |
 | Immunofluorescence analysis of U2OS cells using BTG1 antibody (CAB6359). |
View AllClose