Anti-BTF3 Antibody (CAB15259)
- SKU:
- CAB15259
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-BTF3 Antibody |
抗体コード: | CAB15259 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human BTF3 (NP_001198.2). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Jurkat, MCF7, Mouse testis, Mouse brain, Rat testis |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human BTF3 (NP_001198.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | KLGV NNIS GIEE VNMF TNQG TVIH FNNP KVQA SLAA NTFT ITGH AETK QLTE MLPS ILNQ LGAD SLTS LRRL AEAL PKQS VDGK APLA TGED DDDE VPDL V |
遺伝子ID: | 689 |
Uniprot: | P20290 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 17kDa/22kDa |
観察された分子量: | 22kDa |
同義語: | BTF3, BETA-NAC, BTF3a, BTF3b, NACB |
バックグラウンド: | This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. |
UniProt Protein Function: | BTF3: a general transcription factor. BTF3 can form a stable complex with RNA polymerase II. An interaction partner of protein kinase CK2. Required for the initiation of transcription. Expressed at high levels in glioblastoma multiforme. Overexpressed in the microsatellite instability (MIN) phenotypes in colorectal cancer. Up-regulated strongly in the mammary gland during pregnancy, suggesting an involvement in alveolar growth. Two alternatively spliced isoforms have been described. |
UniProt Protein Details: | Protein type:Transcription factor; Transcription initiation complex Chromosomal Location of Human Ortholog: 5q13.2 Molecular Function:protein binding Biological Process: transcription from RNA polymerase II promoter |
NCBI Summary: | This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008] |
UniProt Code: | P20290 |
NCBI GenInfo Identifier: | 115143 |
NCBI Gene ID: | 689 |
NCBI Accession: | P20290.1 |
UniProt Secondary Accession: | P20290,Q13893, Q76M56, A8K510, |
UniProt Related Accession: | P20290 |
Molecular Weight: | 17,699 Da |
NCBI Full Name: | Transcription factor BTF3 |
NCBI Synonym Full Names: | basic transcription factor 3 |
NCBI Official Symbol: | BTF3 |
NCBI Official Synonym Symbols: | NACB; BTF3a; BTF3b; BETA-NAC |
NCBI Protein Information: | transcription factor BTF3 |
UniProt Protein Name: | Transcription factor BTF3 |
UniProt Synonym Protein Names: | Nascent polypeptide-associated complex subunit beta; NAC-beta; RNA polymerase B transcription factor 3 |
Protein Family: | Basic transcription factor |
UniProt Gene Name: | BTF3 |
UniProt Entry Name: | BTF3_HUMAN |
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