バックグラウンド: | The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O60885-2 |
NCBI GenInfo Identifier: | 7657218 |
NCBI Gene ID: | 23476 |
NCBI Accession: | NP_055114.1 |
UniProt Secondary Accession: | O60885-2,O60433, Q4G0X8, Q86YS8, Q96PD3 |
UniProt Related Accession: | O60885-2,O60885 |
Molecular Weight: | 152kDa |
NCBI Full Name: | bromodomain-containing protein 4 isoform short |
NCBI Synonym Full Names: | bromodomain containing 4 |
NCBI Official Symbol: | BRD4 |
NCBI Official Synonym Symbols: | CAP; MCAP; HUNK1; HUNKI |
NCBI Protein Information: | bromodomain-containing protein 4; bromodomain-containing 4; chromosome-associated protein |
UniProt Protein Name: | Bromodomain-containing protein 4 |
UniProt Synonym Protein Names: | Protein HUNK1 |
Protein Family: | Bromodomain-containing protein |
UniProt Gene Name: | BRD4 |
UniProt Entry Name: | BRD4_HUMAN |