Anti-BMP2K Antibody (CAB15860)
- SKU:
- CAB15860
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-BMP2K Antibody |
| 抗体コード: | CAB15860 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-420 of human BMP2K (NP_060063.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-420 of human BMP2K (NP_060063.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SDNV WEVL ILME YCRA GQVV NQMN KKLQ TGFT EPEV LQIF CDTC EAVA RLHQ CKTP IIHR DLKV ENIL LNDG GNYV LCDF GSAT NKFL NPQK DGVN VVEE EIKK YTTL SYRA PEMI NLYG GKPI TTKA DIWA LGCL LYKL CFFT LPFG ESQV AICD GNFT IPDN SRYS RNIH CLIR FMLE PDPE HRPD IFQV SYFA FKFA KKDC PVSN INNS SIPS ALPE PMTA SEAA ARKS QIKA RITD TIGP TETS IAPR QRPK ANSA TTAT PSVL TIQS SATP VKVL APGE FGNH RPKG ALRP GNGP E |
| 遺伝子ID: | 55589 |
| Uniprot: | Q9NSY1 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 73kDa/75kDa/129kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | BMP2K, BIKE, HRIHFB2017 |
| バックグラウンド: | This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | BIKE: May be involved in osteoblast differentiation. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein kinase, Other; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Other group; NAK family Chromosomal Location of Human Ortholog: 4q21.21 Cellular Component: nucleoplasm; nucleus Molecular Function:phosphatase regulator activity; protein serine/threonine kinase activity Biological Process: protein amino acid phosphorylation; regulation of bone mineralization |
| NCBI Summary: | This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NSY1 |
| NCBI GenInfo Identifier: | 34222653 |
| NCBI Gene ID: | 55589 |
| NCBI Accession: | Q9NSY1.2 |
| UniProt Secondary Accession: | Q9NSY1,O94791, Q4W5H2, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8 |
| UniProt Related Accession: | Q9NSY1 |
| Molecular Weight: | 75,812 Da |
| NCBI Full Name: | BMP-2-inducible protein kinase |
| NCBI Synonym Full Names: | BMP2 inducible kinase |
| NCBI Official Symbol: | BMP2K |
| NCBI Official Synonym Symbols: | BIKE; HRIHFB2017 |
| NCBI Protein Information: | BMP-2-inducible protein kinase |
| UniProt Protein Name: | BMP-2-inducible protein kinase |
| Protein Family: | BMP-2-inducible protein kinase |
| UniProt Gene Name: | BMP2K |
| UniProt Entry Name: | BMP2K_HUMAN |
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