Anti-BICD2 Antibody (CAB10292)
- SKU:
- CAB10292
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-BICD2 Antibody |
抗体コード: | CAB10292 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-620 of human BICD2 (NP_001003800.1). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, HL-60, HeLa, Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-620 of human BICD2 (NP_001003800.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | HVAV AEAG ELRE QLKA LRST HEAR EAQH AEEK GRYE AEGQ ALTE KVSL LEKA SRQD RELL ARLE KELK KVSD VAGE TQGS LSVA QDEL VTFS EELA NLYH HVCM CNNE TPNR VMLD YYRE GQGG AGRT SPGG RTSP EARG RRSP ILLP KGLL APEA GRAD GGTG DSSP SPGS SLPS PLSD P |
遺伝子ID: | 23299 |
Uniprot: | Q8TD16 |
セルラーロケーション: | Cytoplasm, Golgi apparatus, cytoskeleton |
計算された分子量: | 93kDa/96kDa |
観察された分子量: | 118kDa |
同義語: | BICD2, SMALED2, bA526D8.1 |
バックグラウンド: | This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. |
UniProt Protein Function: | BICD2: May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. Belongs to the BicD family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 9q22.31 Cellular Component: annulate lamellae; cytoplasmic vesicle; cytosol; Golgi apparatus; nuclear envelope; nuclear pore; plasma membrane Molecular Function:protein binding; Rab GTPase binding Biological Process: centrosome localization; protein targeting to Golgi; retrograde vesicle-mediated transport, Golgi to ER Disease: Spinal Muscular Atrophy, Lower Extremity-predominant, 2, Autosomal Dominant |
NCBI Summary: | This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8TD16 |
NCBI GenInfo Identifier: | 34098604 |
NCBI Gene ID: | 23299 |
NCBI Accession: | Q8TD16.1 |
UniProt Secondary Accession: | Q8TD16,O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561 |
UniProt Related Accession: | Q8TD16 |
Molecular Weight: | 94kDa |
NCBI Full Name: | Protein bicaudal D homolog 2 |
NCBI Synonym Full Names: | BICD cargo adaptor 2 |
NCBI Official Symbol: | BICD2 |
NCBI Official Synonym Symbols: | SMALED2; bA526D8.1 |
NCBI Protein Information: | protein bicaudal D homolog 2 |
UniProt Protein Name: | Protein bicaudal D homolog 2 |
Protein Family: | Protein bicaudal |
UniProt Gene Name: | BICD2 |
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