Anti-BES1 Antibody (CAB16262)

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SKU:
CAB16262
Product type:
Antibody
Reactivity:
Arabidopsis thaliana
Reactivity:
Rice
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
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Description

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抗体名:Anti-BES1 Antibody
抗体コード:CAB16262
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Arabidopsis thaliana, Rice
宿主種:Rabbit
免疫原:Recombinant protein of human BES1
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Arabidopsis thaliana, Rice
ポジティブサンプル:
免疫原:Recombinant protein of human BES1
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:838518
Uniprot:Q9LN63
セルラーロケーション:
計算された分子量:36kDa
観察された分子量:Refer to figures
同義語:BES1, BZR2, 107 PROTEIN, BRASSINAZOLE-RESISTANT 2, BRI1-EMS-SUPPRESSOR 1, F18O14.7, F18O14_7
バックグラウンド:Encodes brassinosteroid (BR) signalling protein that accumulates in the nucleus as dephosphorylated form in response to BRs. Is phosphorylated by the BIN2 GSK3 kinase. It synergistically interacts with BIM1 to bind to E box sequences (CANNTG). The protein contains a nuclear localization signal (NLS), followed by a highly conserved amino-terminal domain (N) shared by all family members, a BIN2 phosphorylation domain (P), a PEST motif, involved in protein degradation in the absence of BR, and a carboxyl-terminal domain. BES1 can interact with the ELF6 and REF6 Jumonji N/C-domain containing proteins and may direct them to modify histone methylation upstream of some brassinosteroid responsive-genes. Works with BRAVO to regulate QC division in the root.
UniProt Protein Function:Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610).
NCBI Summary:Encodes brassinosteroid (BR) signalling protein that accumulates in the nucleus as dephosphorylated form in response to BRs. Is phosphorylated by the BIN2 GSK3 kinase. It synergistically interacts with BIM1 to bind to E box sequences (CANNTG). The protein contains a nuclear localization signal (NLS), followed by a highly conserved amino-terminal domain (N) shared by all family members, a BIN2 phosphorylation domain (P), a PEST motif, involved in protein degradation in the absence of BR, and a carboxyl-terminal domain. BES1 can interact with the ELF6 and REF6 Jumonji N/C-domain containing proteins and may direct them to modify histone methylation upstream of some brassinosteroid responsive-genes. Works with BRAVO to regulate QC division in the root.
UniProt Code:Q9LN63
NCBI GenInfo Identifier:57012618
NCBI Gene ID:838518
NCBI Accession:Q9LN63.1
UniProt Secondary Accession:Q9LN63,Q8LCX8, Q94JU1, Q9SEG5,
UniProt Related Accession:Q9LN63
Molecular Weight:335 aa
NCBI Full Name:Protein BRASSINAZOLE-RESISTANT 2
NCBI Official Symbol:BES1  
NCBI Official Synonym Symbols:107 PROTEIN; BRASSINAZOLE-RESISTANT 2; BRI1-EMS-SUPPRESSOR 1; BZR2; F18O14.7; F18O14_7  
NCBI Protein Information:Brassinosteroid signaling positive regulator (BZR1) family protein
UniProt Protein Name:Protein BRASSINAZOLE-RESISTANT 2
UniProt Synonym Protein Names:Protein 107; Protein BIN2 SUBSTRATE 1
Protein Family:Protein
UniProt Gene Name:BZR2  
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