Anti-BCL3 Antibody (CAB11582)
- SKU:
- CAB11582
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-BCL3 Antibody |
抗体コード: | CAB11582 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human BCL3 (NP_005169.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Raji, 293T |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human BCL3 (NP_005169.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ANVN AQMY SGSS ALHS ASGR GLLP LVRT LVRS GADS SLKN CHND TPLM VARS RRVI DILR GKAT RPAS TSQP DPSP DRSA NTSP ESSS RLSS NGLL SASP S |
遺伝子ID: | 602 |
Uniprot: | P20749 |
セルラーロケーション: | Cytoplasm, Nucleus, perinuclear region |
計算された分子量: | 47kDa |
観察された分子量: | 60kDa |
同義語: | BCL3, BCL4, D19S37 |
バックグラウンド: | This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. |
UniProt Protein Function: | Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation. |
NCBI Summary: | This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008] |
UniProt Code: | P20749 |
NCBI GenInfo Identifier: | 294862410 |
NCBI Gene ID: | 602 |
NCBI Accession: | P20749.2 |
UniProt Related Accession: | P20749 |
Molecular Weight: | 48kDa |
NCBI Full Name: | B-cell lymphoma 3 protein |
NCBI Synonym Full Names: | B-cell CLL/lymphoma 3 |
NCBI Official Symbol: | BCL3 |
NCBI Official Synonym Symbols: | BCL4; D19S37 |
NCBI Protein Information: | B-cell lymphoma 3 protein |
UniProt Protein Name: | B-cell lymphoma 3 protein |
UniProt Synonym Protein Names: | Proto-oncogene BCL3 |
Protein Family: | B-cell lymphoma 3 protein |
UniProt Gene Name: | BCL3 |
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