Anti-BCAS3 Antibody (CAB7274)
- SKU:
- CAB7274
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Description
| 抗体名: | Anti-BCAS3 Antibody |
| 抗体コード: | CAB7274 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF IP |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 674-913 of human BCAS3 (NP_060149.3). |
| 申し込み: | WB IHC IF IP |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, BT474, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 674-913 of human BCAS3 (NP_060149.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LAGL VPPG SPGP ITRH GSYD SLAS DHSG QEDE EWLS QVEI VTHT GPHR RLWM GPQF QFKT IHPS GQTT VISS SSSV LQSH GPSD TPQP LLDF DTDD LDLN SLRI QPVR SDPV SMPG SSRP VSDR RGVS TVID AASG TFDR SVTL LEVC GSWP EGFG LRHM SSME HTEE GLRE RLAD AMAE SPSR DVVG SGTE LQRE GSIE TLSN SSGS TSGS IPRN FDGY RSPL PTNE SQPL SLFP TGFP |
| 遺伝子ID: | 54828 |
| Uniprot: | Q9H6U6 |
| セルラーロケーション: | Cytoplasm, Nucleus, cytoskeleton |
| 計算された分子量: | 74kDa/99kDa/101kDa/102kDa/103kDa |
| 観察された分子量: | 115kDa |
| 同義語: | BCAS3, GAOB1, MAAB |
| バックグラウンド: |
| UniProt Protein Function: | BCAS3: A chromosomal aberration involving BCAS3 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS4. Belongs to the WD repeat BCAS3 family. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Oncoprotein Chromosomal Location of Human Ortholog: 17q23 Cellular Component: intermediate filament cytoskeleton; cytoplasmic microtubule; leading edge; cytoplasm; nucleus Molecular Function:histone acetyltransferase binding; protein binding; histone binding; beta-tubulin binding; chromatin binding; transcription factor binding; nuclear hormone receptor binding Biological Process: response to starvation; vesicle-mediated transport; positive regulation of filopodium formation; positive regulation of catalytic activity; microtubule organizing center organization and biogenesis; transcription, DNA-dependent; negative regulation of focal adhesion formation; positive regulation of transcription from RNA polymerase II promoter; lumen formation; angiogenesis; Golgi organization and biogenesis |
| UniProt Code: | Q9H6U6 |
| NCBI GenInfo Identifier: | 313104248 |
| NCBI Gene ID: | 54828 |
| NCBI Accession: | Q9H6U6.3 |
| UniProt Secondary Accession: | Q9H6U6,Q17RM0, Q6KF21, Q8IXI6, Q8NDR8, Q8TDL9, Q8TDM1 Q8WY55, Q9BVF0, Q9H957, Q9H9Y9, Q9NXP4, |
| UniProt Related Accession: | Q9H6U6 |
| Molecular Weight: | 928 |
| NCBI Full Name: | Breast carcinoma-amplified sequence 3 |
| NCBI Synonym Full Names: | breast carcinoma amplified sequence 3 |
| NCBI Official Symbol: | BCAS3 |
| NCBI Official Synonym Symbols: | MAAB; GAOB1 |
| NCBI Protein Information: | breast carcinoma-amplified sequence 3; protein Maab1; BCAS4/BCAS3 fusion; metastasis associated antigen of breast cancer; breast carcinoma amplified sequence 4/3 fusion protein |
| UniProt Protein Name: | Breast carcinoma-amplified sequence 3 |
| UniProt Synonym Protein Names: | GAOB1 |
| Protein Family: | Breast carcinoma-amplified sequence |
| UniProt Gene Name: | BCAS3 |
| UniProt Entry Name: | BCAS3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using BCAS3 antibody (CAB7274) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human kidney cancer using BCAS3 antibody (CAB7274) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using BCAS3 antibody (CAB7274) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using BCAS3 antibody (CAB7274) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of A-549 cells using BCAS3 antibody (CAB7274). Blue: DAPI for nuclear staining. |