Anti-BAG2 Antibody (CAB8775)
- SKU:
- CAB8775
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- BAG-2
- Synonyms:
- dJ417I1.2
Frequently bought together:
Description
| 抗体名: | BAG2 Rabbit mAb |
| 抗体コード: | CAB8775 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | BAG-2, dJ417I1.2 |
| 申し込み: | WB, IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human BAG2 |
| 申し込み: | WB, IHC |
| 推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, PC-3, Jurkat |
| 免疫原: | A synthesized peptide derived from human BAG2 |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 9532 |
| Uniprot: | O95816 |
| 計算された分子量: | 24kDa |
| 観察された分子量: | 24KDa |
| UniProt Protein Function: | BAG2: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. |
| UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 6p12.1-p11.2 Cellular Component: cytosol Molecular Function:adenyl-nucleotide exchange factor activity; identical protein binding; protein binding Biological Process: protein folding; protein metabolic process |
| NCBI Summary: | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95816 |
| NCBI GenInfo Identifier: | 12229698 |
| NCBI Gene ID: | 9532 |
| NCBI Accession: | O95816.1 |
| UniProt Secondary Accession: | O95816,Q08AS9, Q6FID0, B4DXE2, |
| UniProt Related Accession: | O95816 |
| Molecular Weight: | 20,189 Da |
| NCBI Full Name: | BAG family molecular chaperone regulator 2 |
| NCBI Synonym Full Names: | BCL2 associated athanogene 2 |
| NCBI Official Symbol: | BAG2 |
| NCBI Official Synonym Symbols: | BAG-2; dJ417I1.2 |
| NCBI Protein Information: | BAG family molecular chaperone regulator 2 |
| UniProt Protein Name: | BAG family molecular chaperone regulator 2 |
| UniProt Synonym Protein Names: | Bcl-2-associated athanogene 2 |
| Protein Family: | BAG family molecular chaperone regulator |
| UniProt Gene Name: | BAG2 |
| UniProt Entry Name: | BAG2_HUMAN |