Anti-Bad Antibody (CAB0741)
- SKU:
- CAB0741
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-Bad Antibody |
| 抗体コード: | CAB0741 |
| 抗体サイズ: | 100µL |
| 申し込み: | WB IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of mouse Bad |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:100 - 1:200 IHC 1:50 - 1:100 |
| 反応性: | Human |
| ポジティブサンプル: | HepG2, HeLa, Jurkat |
| 免疫原: | A synthetic peptide of mouse Bad |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 12015 |
| Uniprot: | |
| セルラーロケーション: | Cytoplasm, Mitochondrion outer membrane |
| 計算された分子量: | 18kDa |
| 観察された分子量: | 15kDa |
| 同義語: | BAD, BBC2, BCL2L8 |
| バックグラウンド: | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
 | Western blot analysis of extracts of various cell lines, using Bad antibody (CAB0741) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |