Anti-B4GALNT1 Antibody (CAB3874)

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SKU:
CAB3874
Product type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-B4GALNT1 Antibody
抗体コード:CAB3874
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IHC
反応性:Human
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 26-240 of human B4GALNT1 (NP_001263398.1).
申し込み:WB IHC
推奨希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:100
反応性:Human
ポジティブサンプル:U-87MG, A375, MCF7
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 26-240 of human B4GALNT1 (NP_001263398.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:STRD APGL RLPL APWA PPQS PRRP ELPD LAPE PRYA HIPV RIKE QVVG LLAW NNCS CESS GGGL PLPF QKQV RAID LTKA FDPA ELRA ASAT REQE FQAF LSRS QSPA DQLL IAPA NSPL QYPL QGVE VQPL RSIL VPGL SLQA ASGQ EVYQ VNLT ASLG TWDV AGEV TGVT LTGE GQAD LTLV SPGL DQLN RQLQ LVTY SSRS YQTN TADT GAR
遺伝子ID:2583
Uniprot:Q00973
セルラーロケーション:Golgi apparatus membrane, Single-pass type II membrane protein
計算された分子量:35kDa/52kDa/58kDa
観察された分子量:80kDa
同義語:B4GALNT1, GALGT, GALNACT, GalNAc-T, SPG26, beta-1
バックグラウンド:GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1, 4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.
UniProt Code:Q00973
NCBI GenInfo Identifier:1168736
NCBI Gene ID:2583
NCBI Accession:Q00973.2
UniProt Secondary Accession:Q00973,Q8N636, B4DE26,
UniProt Related Accession:Q00973
Molecular Weight:533
NCBI Full Name:Beta-1,4 N-acetylgalactosaminyltransferase 1
NCBI Synonym Full Names:beta-1,4-N-acetyl-galactosaminyl transferase 1
NCBI Official Symbol:B4GALNT1  
NCBI Official Synonym Symbols:GALGT; SPG26; GALNACT; GalNAc-T  
NCBI Protein Information:beta-1,4 N-acetylgalactosaminyltransferase 1; beta1,4GalNAc-T; GM2/GD2 synthase; GD2 synthase, GM2 synthase; UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T)
UniProt Protein Name:Beta-1,4 N-acetylgalactosaminyltransferase 1
UniProt Synonym Protein Names:(N-acetylneuraminyl)-galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T
Protein Family:Beta-1,4 N-acetylgalactosaminyltransferase
UniProt Gene Name:B4GALNT1  
UniProt Entry Name:B4GN1_HUMAN
Anti-B4GALNT1 Antibody (CAB3874)Western blot analysis of extracts of various cell lines, using B4GALNT1 antibody (CAB3874) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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