Anti-B3GNT6 Antibody (CAB14975)
- SKU:
- CAB14975
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-B3GNT6 Antibody |
| 抗体コード: | CAB14975 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human B3GNT6 (NP_619651.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Rat |
| ポジティブサンプル: | Rat stomach |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human B3GNT6 (NP_619651.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FLQA PRSP REER SPQE ETPE GPTD APAA DEPP SELV PGPP CVAN ASAN ATAD FEQL PARI QDFL RYRH CRHF PLLW DAPA KCAG GRGV FLLL AVKS APEH YERR ELIR RTWG QERS YGGR PVRR LFLL GTPG PEDE ARAE RLAE LVAL EARE HGDV LQWA FADT FLNL TLK |
| 遺伝子ID: | 192134 |
| Uniprot: | Q6ZMB0 |
| セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
| 計算された分子量: | 29kDa/42kDa |
| 観察された分子量: | 43kDa |
| 同義語: | B3GNT6, B3Gn-T6, BGnT-6, beta-1, 3-Gn-T6 |
| バックグラウンド: | The protein encoded by this gene is a beta-1, 3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. |
| UniProt Protein Function: | B3GNT6: Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs. Belongs to the glycosyltransferase 31 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.4.1.-; Membrane protein, integral; Transferase; Glycan Metabolism - O-glycan biosynthesis Chromosomal Location of Human Ortholog: 11q13.4 Cellular Component: Golgi membrane Molecular Function:galactosyltransferase activity; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Biological Process: O-glycan processing |
| UniProt Code: | Q6ZMB0 |
| NCBI GenInfo Identifier: | 152033628 |
| NCBI Gene ID: | 192134 |
| NCBI Accession: | Q6ZMB0.2 |
| UniProt Secondary Accession: | Q6ZMB0,Q6ZSC5, Q8TAZ4, Q8TDX1, E9PKS1, |
| UniProt Related Accession: | Q6ZMB0 |
| Molecular Weight: | 42,785 Da |
| NCBI Full Name: | Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase |
| NCBI Synonym Full Names: | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 |
| NCBI Official Symbol: | B3GNT6 |
| NCBI Official Synonym Symbols: | BGnT-6; B3Gn-T6; beta3Gn-T6; beta-1,3-Gn-T6 |
| NCBI Protein Information: | acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase |
| UniProt Protein Name: | Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase |
| UniProt Synonym Protein Names: | Core 3 synthase; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6; BGnT-6; Beta-1,3-Gn-T6; Beta-1,3-N-acetylglucosaminyltransferase 6; Beta3Gn-T6 |
| Protein Family: | Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase |
| UniProt Gene Name: | B3GNT6 |
| UniProt Entry Name: | B3GN6_HUMAN |
 | Western blot analysis of extracts of rat stomach, using B3GNT6 antibody (CAB14975) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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