Anti-AVPR1A Antibody (CAB8400)
- SKU:
- CAB8400
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-AVPR1A Antibody |
抗体コード: | CAB8400 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 349-418 of human AVPR1A (NP_000697.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, A-549, Mouse liver, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 349-418 of human AVPR1A (NP_000697.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MFFS GHLL QDCV QSFP CCQN MKEK FNKE DTDS MSRR QTFY SNNR SPTN STGM WKDS PKSS KSIK FIPV ST |
遺伝子ID: | 552 |
Uniprot: | P37288 |
セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
計算された分子量: | 46kDa |
観察された分子量: | 60kDa |
同義語: | AVPR1A, AVPR V1a, AVPR1, V1aR, AVPRV1a |
バックグラウンド: | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. |
UniProt Protein Function: | AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q14-q15 Cellular Component: endosome; integral to plasma membrane; plasma membrane Molecular Function:peptide binding; protein binding; protein kinase C binding Biological Process: blood circulation; cellular response to hormone stimulus; generation of precursor metabolites and energy; maternal behavior; phospholipase C activation; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin |
NCBI Summary: | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P37288 |
NCBI GenInfo Identifier: | 586197 |
NCBI Gene ID: | 552 |
NCBI Accession: | P37288.1 |
UniProt Related Accession: | P37288 |
Molecular Weight: | 46,800 Da |
NCBI Full Name: | Vasopressin V1a receptor |
NCBI Synonym Full Names: | arginine vasopressin receptor 1A |
NCBI Official Symbol: | AVPR1A |
NCBI Official Synonym Symbols: | V1aR; AVPR1; AVPR V1a |
NCBI Protein Information: | vasopressin V1a receptor |
UniProt Protein Name: | Vasopressin V1a receptor |
UniProt Synonym Protein Names: | AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor |
Protein Family: | Vasopressin V1a receptor |
UniProt Gene Name: | AVPR1A |
UniProt Entry Name: | V1AR_HUMAN |
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