Anti-AURKC Antibody (CAB16977)
- SKU:
- CAB16977
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-AURKC Antibody |
| 抗体コード: | CAB16977 |
| 抗体サイズ: | 20uL, 50 uL |
| 申し込み: | IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human AURKC (NP_001015878.1). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human AURKC (NP_001015878.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSSP RAVV QLGK AQPA GEEL ATAN QTAQ QPSS PAMR RLTV DDFE IGRP LGKG KFGN VYLA RLKE SHFI VALK VLFK SQIE KEGL EHQL RREI EIQA HLQH |
| 遺伝子ID: | 6795 |
| Uniprot: | Q9UQB9 |
| セルラーロケーション: | |
| 計算された分子量: | 32kDa/33kDa/35kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | AURKC, AIE2, AIK3, ARK3, AurC, HEL-S-90, SPGF5, STK13, aurora-C |
| バックグラウンド: | This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | AurC: a member of the AUR family of kinases. May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. Localized to centrosome from anaphase to cytokinesis. Two splice-variant isoforms have been described. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, Other; EC 2.7.11.1; Other group; AUR family Chromosomal Location of Human Ortholog: 19q13.43 Cellular Component: condensed chromosome; condensed nuclear chromosome, pericentric region; midbody; spindle; spindle microtubule; spindle midzone; spindle pole centrosome Molecular Function:histone serine kinase activity; protein kinase activity; protein serine/threonine/tyrosine kinase activity Biological Process: attachment of spindle microtubules to kinetochore; histone modification; positive regulation of cytokinesis; protein amino acid phosphorylation; spindle midzone assembly involved in mitosis Disease: Spermatogenic Failure 5 |
| NCBI Summary: | This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UQB9 |
| NCBI GenInfo Identifier: | 27805738 |
| NCBI Gene ID: | 6795 |
| NCBI Accession: | Q9UQB9.1 |
| UniProt Secondary Accession: | Q9UQB9,O60681, O75442, Q6AZY8, Q6DLZ0, Q9UPK5, |
| UniProt Related Accession: | Q9UQB9 |
| Molecular Weight: | 33,672 Da |
| NCBI Full Name: | Aurora kinase C |
| NCBI Synonym Full Names: | aurora kinase C |
| NCBI Official Symbol: | AURKC |
| NCBI Official Synonym Symbols: | AIE2; AIK3; ARK3; AurC; SPGF5; STK13; HEL-S-90; aurora-C |
| NCBI Protein Information: | aurora kinase C |
| UniProt Protein Name: | Aurora kinase C |
| UniProt Synonym Protein Names: | Aurora 3; Aurora/IPL1-related kinase 3; ARK-3; Aurora-related kinase 3; Aurora/IPL1/Eg2 protein 2; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C |
| Protein Family: | Aurora kinase |
| UniProt Gene Name: | AURKC |
| UniProt Entry Name: | AURKC_HUMAN |