Anti-ATP8A1 Antibody (CAB3369)
- SKU:
- CAB3369
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-ATP8A1 Antibody |
抗体コード: | CAB3369 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-545 of human ATP8A1 (NP_001098999.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-545 of human ATP8A1 (NP_001098999.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | QFKK CTIA GVAY GQNS QFGD EKTF SDSS LLEN LQNN HPTA PIIC EFLT MMAV CHTA VPER EGDK IIYQ AASP DEGA LVRA AKQL NFVF TGRT PDSV IIDS LGQE ERYE LLNV LEFT SARK RMSV IV |
遺伝子ID: | 10396 |
Uniprot: | Q9Y2Q0 |
セルラーロケーション: | Cell membrane, Cytoplasmic granule, Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Multi-pass membrane protein, chromaffin granule membrane, secretory vesicle |
計算された分子量: | 129kDa/131kDa |
観察された分子量: | 170kDa |
同義語: | ATP8A1, ATPASEII, ATPIA, ATPP2 |
バックグラウンド: | The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | ATP8A1: May play a role in the transport of aminophospholipids from the outer to the inner leaflet of various membranes and the maintenance of asymmetric distribution of phospholipids, mainly in secretory vesicles. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transporter; EC 3.6.3.1; Hydrolase; Membrane protein, multi-pass; Membrane protein, integral; Transporter, ion channel Chromosomal Location of Human Ortholog: 4p13 Cellular Component: Golgi apparatus; membrane; endoplasmic reticulum; plasma membrane; integral to membrane Molecular Function:phospholipid-translocating ATPase activity; protein binding; magnesium ion binding; ATP binding; cation-transporting ATPase activity Biological Process: phospholipid translocation; metabolic process; learning; transmembrane transport; cation transport; positive regulation of cell migration |
NCBI Summary: | The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y2Q0 |
NCBI GenInfo Identifier: | 8134331 |
NCBI Gene ID: | 10396 |
NCBI Accession: | Q9Y2Q0.1 |
UniProt Secondary Accession: | Q9Y2Q0,Q32M35, Q32M36, Q4W5J7, Q4W5P2, |
UniProt Related Accession: | Q9Y2Q0 |
Molecular Weight: | 1164 |
NCBI Full Name: | Phospholipid-transporting ATPase IA |
NCBI Synonym Full Names: | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
NCBI Official Symbol: | ATP8A1 |
NCBI Official Synonym Symbols: | ATPIA; ATPP2; ATPASEII |
NCBI Protein Information: | phospholipid-transporting ATPase IA; ATPase II; chromaffin granule ATPase II; aminophospholipid translocase; ATPase class I type 8A member 1; probable phospholipid-transporting ATPase IA; P4-ATPase flippase complex alpha subunit ATP8A1 |
UniProt Protein Name: | Phospholipid-transporting ATPase IA |
UniProt Synonym Protein Names: | ATPase class I type 8A member 1; Chromaffin granule ATPase II; P4-ATPase flippase complex alpha subunit ATP8A1 |
Protein Family: | Phospholipid-transporting ATPase |
UniProt Gene Name: | ATP8A1 |
UniProt Entry Name: | AT8A1_HUMAN |
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