Anti-ATP5I Antibody (CAB16769)
- SKU:
- CAB16769
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-ATP5I Antibody |
抗体コード: | CAB16769 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human ATP5I (NP_009031.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, LO2, 293T, HeLa |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human ATP5I (NP_009031.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MVPP VQVS PLIK LGRY SALF LGVA YGAT RYNY LKPR AEEE RRIA AEEK KKQD ELKR IARE LAED DSIL K |
遺伝子ID: | 521 |
Uniprot: | P56385 |
セルラーロケーション: | Mitochondrion, Mitochondrion inner membrane |
計算された分子量: | 7kDa |
観察された分子量: | Refer to figures |
同義語: | ATP5I, ATP5K |
バックグラウンド: | Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | ATP5I: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. Belongs to the ATPase e subunit family. |
UniProt Protein Details: | Protein type:EC 3.6.3.14; Energy Metabolism - oxidative phosphorylation; Mitochondrial Chromosomal Location of Human Ortholog: 4p16.3 Cellular Component: mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrion Molecular Function:ATPase activity; hydrogen ion transmembrane transporter activity; transmembrane transporter activity Biological Process: cellular metabolic process; mitochondrial ATP synthesis coupled proton transport |
NCBI Summary: | Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010] |
UniProt Code: | P56385 |
NCBI GenInfo Identifier: | 3023369 |
NCBI Gene ID: | 521 |
NCBI Accession: | P56385.2 |
UniProt Secondary Accession: | P56385,Q0D2L9, |
UniProt Related Accession: | P56385 |
Molecular Weight: | 7,933 Da |
NCBI Full Name: | ATP synthase subunit e, mitochondrial |
NCBI Synonym Full Names: | ATP synthase, H+ transporting, mitochondrial Fo complex subunit E |
NCBI Official Symbol: | ATP5I |
NCBI Official Synonym Symbols: | ATP5K |
NCBI Protein Information: | ATP synthase subunit e, mitochondrial |
UniProt Protein Name: | ATP synthase subunit e, mitochondrial |
Protein Family: | ATP synthase |
UniProt Gene Name: | ATP5I |
UniProt Entry Name: | ATP5I_HUMAN |