Anti-ATP4B Antibody (CAB10106)
- SKU:
- CAB10106
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ATP4B Antibody |
| 抗体コード: | CAB10106 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human ATP4B (NP_000696.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | LO2, SW620, NCI-H460, Mouse small intestine, Mouse liver, Mouse heart, Mouse pancreas, Rat stomach |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human ATP4B (NP_000696.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LMQT VDPY TPDY QDQL RSPG VTLR PDVY GEKG LEIV YNVS DNRT WADL TQTL HAFL AGYS PAAQ EDSI NCTS EQYF FQES FRAP NHTK FSCK FTAD MLQN CSGL ADPN FGFE EGKP CFII KMNR IVKF LPSN GSAP RVDC AFLD QPRE LGQP LQVK YYPP NGTF SLHY FPYY GKKA QPHY SNPL VAAK LLNI PRNA EVAI VCKV MAEH VTFN NPHD PYEG KVEF KLKI EK |
| 遺伝子ID: | 496 |
| Uniprot: | P51164 |
| セルラーロケーション: | Cell membrane, Single-pass type II membrane protein |
| 計算された分子量: | 33kDa |
| 観察された分子量: | 35kDa |
| 同義語: | ATP4B, ATP6B |
| バックグラウンド: | The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. |
| UniProt Protein Function: | ATP4B: belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 13q34 Cellular Component: plasma membrane Molecular Function:hydrogen:potassium-exchanging ATPase activity; protein binding |
| NCBI Summary: | The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P51164 |
| NCBI GenInfo Identifier: | 1703461 |
| NCBI Gene ID: | 496 |
| NCBI Accession: | P51164.1 |
| UniProt Secondary Accession: | P51164,B1B0N8, |
| UniProt Related Accession: | P51164 |
| Molecular Weight: | 33,367 Da |
| NCBI Full Name: | Potassium-transporting ATPase subunit beta |
| NCBI Synonym Full Names: | ATPase H+/K+ transporting beta subunit |
| NCBI Official Symbol: | ATP4B |
| NCBI Official Synonym Symbols: | ATP6B |
| NCBI Protein Information: | potassium-transporting ATPase subunit beta |
| UniProt Protein Name: | Potassium-transporting ATPase subunit beta |
| UniProt Synonym Protein Names: | Gastric H(+)/K(+) ATPase subunit beta; Proton pump beta chain |
| Protein Family: | Potassium-transporting ATPase |
| UniProt Gene Name: | ATP4B |
| UniProt Entry Name: | ATP4B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ATP4B antibody (CAB10106) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human stomach using ATP4B antibody (CAB10106) at dilution of 1:100 (40x lens). |
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