Anti-ATG12 Antibody (CAB19610)
- SKU:
- CAB19610
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Autophagy
Frequently bought together:
Description
| 抗体名: | Anti-ATG12 Antibody |
| 抗体コード: | CAB19610 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human Apg12. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | PC-3, Mouse brain, Mouse stomach |
| 免疫原: | A synthesized peptide derived from human Apg12. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 9140 |
| Uniprot: | O94817 |
| セルラーロケーション: | |
| 計算された分子量: | 22, 55kDa |
| 観察された分子量: | 55KDa |
 | Western blot - ATG12 Rabbit mAb (CAB19610) |
| 同義語: | ATG12, APG12, APG12L, FBR93, HAPG12, Apg12 |
| バックグラウンド: | Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008] |
| UniProt Protein Function: | ATG12: Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5. Ubiquitous. Belongs to the ATG12 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Autophagy; Ubiquitin-like modifier Chromosomal Location of Human Ortholog: 5q22.3 Cellular Component: cytosol; phagocytic vesicle membrane; pre-autophagosomal structure membrane Molecular Function:APG8 conjugating enzyme activity; protein binding Biological Process: autophagic vacuole formation; C-terminal protein lipidation; macroautophagy; mitochondrion degradation |
| NCBI Summary: | Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | O94817 |
| NCBI GenInfo Identifier: | 17366241 |
| NCBI Gene ID: | 9140 |
| NCBI Accession: | O94817.1 |
| UniProt Secondary Accession: | O94817,Q6PJV2, |
| UniProt Related Accession: | O94817 |
| Molecular Weight: | 15kDa |
| NCBI Full Name: | Ubiquitin-like protein ATG12 |
| NCBI Synonym Full Names: | autophagy related 12 |
| NCBI Official Symbol: | ATG12 |
| NCBI Official Synonym Symbols: | APG12; FBR93; APG12L; HAPG12 |
| NCBI Protein Information: | ubiquitin-like protein ATG12 |
| UniProt Protein Name: | Ubiquitin-like protein ATG12 |
| UniProt Synonym Protein Names: | Autophagy-related protein 12; APG12-like |
| Protein Family: | Autophagy protein |
| UniProt Gene Name: | ATG12 |