Anti-ARL4C Antibody (CAB18311)
- SKU:
- CAB18311
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-ARL4C Antibody |
| 抗体コード: | CAB18311 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human ARL4C. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant protein of human ARL4C. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 10123 |
| Uniprot: | P56559 |
| セルラーロケーション: | |
| 計算された分子量: | 21kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | ARL4C, ARL7, LAK |
| バックグラウンド: | ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. |
| UniProt Protein Function: | ARL4C: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP- bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process. Belongs to the small GTPase superfamily. Arf family. |
| UniProt Protein Details: | Protein type:G protein; G protein, monomeric, ARF; G protein, monomeric Chromosomal Location of Human Ortholog: 2q37.1 Cellular Component: cytoplasm; plasma membrane; nucleus; filopodium Molecular Function:GTPase activity; protein binding; GTP binding; alpha-tubulin binding Biological Process: metabolic process; small GTPase mediated signal transduction; endocytic recycling |
| NCBI Summary: | ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P56559 |
| NCBI GenInfo Identifier: | 540344578 |
| NCBI Gene ID: | 10123 |
| NCBI Accession: | NP_001269360.1 |
| UniProt Secondary Accession: | P56559,Q4A519, Q53R10, Q9BVN1, Q9UQ34, |
| UniProt Related Accession: | P56559 |
| Molecular Weight: | 22,448 Da |
| NCBI Full Name: | ADP-ribosylation factor-like protein 4C isoform 1 |
| NCBI Synonym Full Names: | ADP-ribosylation factor-like 4C |
| NCBI Official Symbol: | ARL4C |
| NCBI Official Synonym Symbols: | LAK; ARL7 |
| NCBI Protein Information: | ADP-ribosylation factor-like protein 4C; ADP-ribosylation factor-like 7; ADP ribosylation factor-like protein 7; ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK |
| UniProt Protein Name: | ADP-ribosylation factor-like protein 4C |
| UniProt Synonym Protein Names: | ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK |
| Protein Family: | ADP-ribosylation factor-like protein |
| UniProt Gene Name: | ARL4C |
| UniProt Entry Name: | ARL4C_HUMAN |