Anti-ARID3A Antibody (CAB7668)
- SKU:
- CAB7668
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-ARID3A Antibody |
| 抗体コード: | CAB7668 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IP |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 324-593 of human ARID3A (NP_005215.1). |
| 申し込み: | WB IHC IP |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:20 - 1:50 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Jurkat, MCF7, Mouse testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 324-593 of human ARID3A (NP_005215.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PYEC EKRG LSNP NELQ AAID SNRR EGRR QSFG GSLF AYSP GGAH GMLS SPKL PVSS LGLA ASTN GSSI TPAP KIKK EEDS AIPI TVPG RLPV SLAG HPVV AAQA AAVQ AAAA QAAV AAQA AALE QLRE KLES AEPP EKKM ALVA DEQQ RLMQ RALQ QNFL AMAA QLPM SIRI NSQA SESR QDSA VNLT GTNG SNSI SMSV EING IMYT GVLF AQPP APTP TSAP NKGG GGGG GSSS NAGG RGGN TGTS GGQA GPAG LSTP STST SNNS LP |
| 遺伝子ID: | 1820 |
| Uniprot: | Q99856 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 62kDa |
| 観察された分子量: | 95kDa |
| 同義語: | ARID3A, BRIGHT, DRIL1, DRIL3, E2FBP1 |
| バックグラウンド: | This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. |
| UniProt Protein Function: | Bright: a member of the ARID (AT-rich interaction domain) family of transcription factors. It was found by its homology to the Drosophila dead ringer protein, which is important for normal embryogenesis. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association. This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu. Activates E mu-driven transcription by binding these sites. Contributes to localized control of accessibility and therefore nonrandom gene use during V(D)J recombination. |
| UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleolus; lipid raft Molecular Function:protein binding; protein homodimerization activity; chromatin binding Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99856 |
| NCBI GenInfo Identifier: | 12230034 |
| NCBI Gene ID: | 1820 |
| NCBI Accession: | Q99856.2 |
| UniProt Related Accession: | Q99856 |
| Molecular Weight: | |
| NCBI Full Name: | AT-rich interactive domain-containing protein 3A |
| NCBI Synonym Full Names: | AT-rich interaction domain 3A |
| NCBI Official Symbol: | ARID3A |
| NCBI Official Synonym Symbols: | DRIL1; DRIL3; BRIGHT; E2FBP1 |
| NCBI Protein Information: | AT-rich interactive domain-containing protein 3A |
| UniProt Protein Name: | AT-rich interactive domain-containing protein 3A |
| UniProt Synonym Protein Names: | B-cell regulator of IgH transcription; Bright; Dead ringer-like protein 1; E2F-binding protein 1 |
| UniProt Gene Name: | ARID3A |
| UniProt Entry Name: | ARI3A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ARID3A antibody (CAB7668) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat lung using ARID3A Rabbit pAb (CAB7668) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human lung cancer using ARID3A Rabbit pAb (CAB7668) at dilution of 1:100 (40x lens). |
 | Immunoprecipitation analysis of 150ug extracts of MCF7 cells using 3ug ARID3A antibody (CAB7668). Western blot was performed from the immunoprecipitate using ARID3A antibody (CAB7668) at a dilition of 1:500. |
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