Anti-ARID2 Antibody (CAB8601)[KO Validated]
![Anti-ARID2 Antibody (CAB8601)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/608x608/products/18444/18310/anti-arid2-antibody-cab8601ko-validated__33320__10692.1645803965.jpg?c=1 "Anti-ARID2 Antibody (CAB8601)[KO Validated]")
- SKU:
- CAB8601
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
![Anti-ARID2 Antibody (CAB8601)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/1280x1280/products/18444/18310/anti-arid2-antibody-cab8601ko-validated__33320__10692.1645803965.jpg?c=1&imbypass=on "Anti-ARID2 Antibody (CAB8601)[KO Validated]")
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Description
| 抗体名: | Anti-ARID2 Antibody [KO Validated] |
| 抗体コード: | CAB8601 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1586-1835 of human ARID2 (NP_689854.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | LO2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1586-1835 of human ARID2 (NP_689854.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | QNVV PQNT PMPP SPAV QVQG QPNS SQPS PFSG SSQP GDPM RKPG QNFM CLWQ SCKK WFQT PSQV FYHA ATEH GGKD VYPG QCLW EGCE PFQR QRFS FITH LQDK HCSK DALL AGLK QDEP GQAG SQKS STKQ PTVG GTSS TPRA QKAI VNHP SAAL MALR RGSR NLVF RDFT DEKE GPIT KHIR LTAA LILK NIGK YSEC GRRL LKRH ENNL SVLA ISNM EASS TLAK CLYE LNFT VQSK EQEK DSEM LQ |
| 遺伝子ID: | 196528 |
| Uniprot: | Q68CP9 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 191kDa/197kDa |
| 観察された分子量: | 250kDa |
| 同義語: | ARID2, BAF200, p200 |
| バックグラウンド: |
| UniProt Protein Function: | ARID2: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 12q12 Cellular Component: nucleoplasm; plasma membrane Molecular Function:protein binding; DNA binding; metal ion binding Biological Process: regulation of transcription, DNA-dependent; nucleosome disassembly; transcription, DNA-dependent; chromatin modification |
| NCBI Summary: | ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 [PubMed 15985610]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q68CP9 |
| NCBI GenInfo Identifier: | 73921721 |
| NCBI Gene ID: | 196528 |
| NCBI Accession: | Q68CP9.2 |
| UniProt Secondary Accession: | Q68CP9,Q15KG9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28 Q96SJ6, Q9HCL5, |
| UniProt Related Accession: | Q68CP9 |
| Molecular Weight: | 191,422 Da |
| NCBI Full Name: | AT-rich interactive domain-containing protein 2 |
| NCBI Synonym Full Names: | AT rich interactive domain 2 (ARID, RFX-like) |
| NCBI Official Symbol: | ARID2 |
| NCBI Official Synonym Symbols: | p200; BAF200 |
| NCBI Protein Information: | AT-rich interactive domain-containing protein 2; zipzap; zipzap/p200; BRG1-associated factor 200; ARID domain-containing protein 2; zinc finger protein with activation potential |
| UniProt Protein Name: | AT-rich interactive domain-containing protein 2 |
| UniProt Synonym Protein Names: | BRG1-associated factor 200; BAF200; Zinc finger protein with activation potential; Zipzap/p200 |
| Protein Family: | AT-rich interactive domain-containing protein |
| UniProt Gene Name: | ARID2 |
| UniProt Entry Name: | ARID2_HUMAN |
![Anti-ARID2 Polyclonal Antibody [KO Validated] (CAB8601)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/m/254/A8601_1__54090.jpg) | Western blot analysis of extracts of LO2 cells, using ARID2 antibody (CAB8601) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
![Anti-ARID2 Polyclonal Antibody [KO Validated] (CAB8601)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/g/241/A8601_2__66379.jpg) | Western blot analysis of extracts from normal (control) and ARID2 knockout (KO) HeLa cells, using ARID2 antibody (CAB8601) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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