Anti-ARG1 Antibody (CAB4923)
- SKU:
- CAB4923
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-ARG1 Antibody |
| 抗体コード: | CAB4923 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human ARG1 |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Rat liver |
| 免疫原: | A synthesized peptide derived from human ARG1 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 383 |
| Uniprot: | P05089 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 35kDa |
| 観察された分子量: | 40KDa |
| 同義語: | ARG1, arginase-1 |
| バックグラウンド: | Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
| UniProt Protein Function: | ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Amino Acid Metabolism - arginine and proline; EC 3.5.3.1; Hydrolase Chromosomal Location of Human Ortholog: 6q23.2 Cellular Component: cytoplasm; cytosol; extracellular region; nucleus Molecular Function:arginase activity Biological Process: arginine catabolic process; neutrophil degranulation; urea cycle Disease: Argininemia |
| NCBI Summary: | Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
| UniProt Code: | P05089 |
| NCBI GenInfo Identifier: | 12230985 |
| NCBI Gene ID: | 383 |
| NCBI Accession: | P05089.2 |
| UniProt Secondary Accession: | P05089,Q5JWT5, Q5JWT6, Q8TE72, Q9BS50, A6NEA0, |
| UniProt Related Accession: | P05089 |
| Molecular Weight: | 35kDa |
| NCBI Full Name: | Arginase-1 |
| NCBI Synonym Full Names: | arginase 1 |
| NCBI Official Symbol: | ARG1 |
| NCBI Protein Information: | arginase-1 |
| UniProt Protein Name: | Arginase-1 |
| UniProt Synonym Protein Names: | Liver-type arginase; Type I arginase |
| Protein Family: | Arginase |
| UniProt Gene Name: | ARG1 |
 | Western blot - ARG1 Rabbit mAb (CAB4923) |
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