Anti-ARFGEF1 Antibody (CAB16483)
- SKU:
- CAB16483
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ARFGEF1 Antibody |
| 抗体コード: | CAB16483 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human ARFGEF1 (NP_006412.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | U-87MG, BxPC-3 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human ARFGEF1 (NP_006412.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEKE RHRQ HHHL LQSP VSHH EPES PQLR YLPP QTVD HISQ EHEG DLDL HTND VDKS LQDD TEPE NGSD ISSA ENEQ TEAD QATA AETL SKNE VLYD GENH DCEE KPQD IVQN IVEE MVNI VVGD MGEG TTIN ASAD GNIG TIED GSDS ENIQ ANGI PGTP ISVA YTPS LPDD RLSV SSND TQES GNSS GPSP GAKF SHIL Q |
| 遺伝子ID: | 10565 |
| Uniprot: | Q9Y6D6 |
| セルラーロケーション: | Cytoplasm, Golgi apparatus, Membrane, Nucleus, Nucleus matrix, nucleolus, perinuclear region, trans-Golgi network |
| 計算された分子量: | 208kDa |
| 観察された分子量: | 200kDa |
| 同義語: | ARFGEF1, ARFGEP1, BIG1, P200 |
| バックグラウンド: | ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition. |
| UniProt Code: | Q9Y6D6 |
| NCBI GenInfo Identifier: | 51479145 |
| NCBI Gene ID: | 10565 |
| NCBI Accession: | NP_006412.2 |
| UniProt Secondary Accession: | Q9Y6D6,Q9NV46, Q9UFV2, Q9UNL0, |
| UniProt Related Accession: | Q59FY5,Q9Y6D6 |
| Molecular Weight: | 208,767 Da |
| NCBI Full Name: | brefeldin A-inhibited guanine nucleotide-exchange protein 1 |
| NCBI Synonym Full Names: | ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) |
| NCBI Official Symbol: | ARFGEF1 |
| NCBI Official Synonym Symbols: | BIG1; P200; ARFGEP1; DKFZP434L057; D730028O18Rik |
| NCBI Protein Information: | brefeldin A-inhibited guanine nucleotide-exchange protein 1; p200 ARF-GEP1; OTTHUMP00000227052; OTTHUMP00000227095; brefeldin A-inhibited GEP 1; p200 ARF guanine nucleotide exchange factor |
| UniProt Protein Name: | Brefeldin A-inhibited guanine nucleotide-exchange protein 1 |
| UniProt Synonym Protein Names: | p200 ARF guanine nucleotide exchange factor; p200 ARF-GEP1 |
| Protein Family: | Brefeldin A-inhibited guanine nucleotide-exchange protein |
| UniProt Gene Name: | ARFGEF1 |
| UniProt Entry Name: | BIG1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ARFGEF1 antibody (CAB16483) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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