Anti-ARF3 Antibody (CAB8101)
- SKU:
- CAB8101
- Product type:
- Antibody
- Application:
- IF
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | ARF3 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8101 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human ARF3 (NP_001650.1). |
| 申し込み: | IF |
| 推奨希釈: | IF 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human ARF3 (NP_001650.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MGNI FGNL LKSL IGKK EMRI LMVG LDAA GKTT ILYK LKLG EIVT TIPT IGFN VETV EYKN ISFT VWDV GGQD KIRP LWRH YFQN TQGL IFVV DSND RERV NEAR EELM RMLA EDEL RDAV LLVF ANKQ DLPN AMNA AEIT DKLG LHSL RHRN WYIQ ATCA TSGD GLYE GLDW LANQ LKNK K |
| 遺伝子ID: | 377 |
| Uniprot: | P61204 |
| セルラーロケーション: | Cytoplasm, Golgi apparatus, perinuclear region |
| 計算された分子量: | 16kDa/20kDa |
| 観察された分子量: |
| 同義語: | ARF3 |
| バックグラウンド: | ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns. |
| UniProt Protein Function: | ARF3: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. |
| UniProt Protein Details: | Protein type:G protein, monomeric, ARF; G protein; G protein, monomeric; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 12q13 Cellular Component: Golgi membrane Molecular Function:GTPase activity Biological Process: phosphatidylinositol biosynthetic process; retrograde vesicle-mediated transport, Golgi to ER |
| NCBI Summary: | ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P61204 |
| NCBI GenInfo Identifier: | 47117657 |
| NCBI Gene ID: | 377 |
| NCBI Accession: | P61204.2 |
| UniProt Secondary Accession: | P61204,P16587, A8K6G8, B7ZB63, |
| UniProt Related Accession: | P61204 |
| Molecular Weight: | 16,145 Da |
| NCBI Full Name: | ADP-ribosylation factor 3 |
| NCBI Synonym Full Names: | ADP ribosylation factor 3 |
| NCBI Official Symbol: | ARF3 |
| NCBI Protein Information: | ADP-ribosylation factor 3 |
| UniProt Protein Name: | ADP-ribosylation factor 3 |
| Protein Family: | Auxin response factor |
| UniProt Gene Name: | ARF3 |
| UniProt Entry Name: | ARF3_HUMAN |
 | Immunofluorescence analysis of U2OS cells using ARF3 antibody (CAB8101) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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