Anti-APPBP2 Antibody (CAB15781)
- SKU:
- CAB15781
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-APPBP2 Antibody |
抗体コード: | CAB15781 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 386-585 of human APPBP2 (NP_006371.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-431, HeLa, Jurkat, Raji, Mouse kidney, Mouse brain, Rat kidney, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 386-585 of human APPBP2 (NP_006371.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LEEI AIDC HNKE TEQR LLQE AHDL HLSS LQLA KKAF GEFN VQTA KHYG NLGR LYQS MRKF KEAE EMHI KAIQ IKEQ LLGQ EDYE VALS VGHL ASLY NYDM NQYE NAEK LYLR SIAI GKKL FGEG YSGL EYDY RGLI KLYN SIGN YEKV FEYH NVLS NWNR LRDR QYSV TDAL EDVS TSPQ STEE VVQS FLIS QNVE GPSC |
遺伝子ID: | 10513 |
Uniprot: | Q92624 |
セルラーロケーション: | Cytoplasm, Membrane, Nucleus, Peripheral membrane protein, cytoskeleton |
計算された分子量: | 66kDa |
観察された分子量: | 67kDa, 71kDa, 80kDa |
同義語: | APPBP2, APP-BP2, HS.84084, PAT1 |
バックグラウンド: | The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | APPBP2: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 17q23.2 Cellular Component: cytoplasm; cytoplasmic vesicle membrane; microtubule; microtubule associated complex; nucleus Molecular Function:microtubule motor activity; protein binding Biological Process: intracellular protein transport; intracellular transport |
NCBI Summary: | The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q92624 |
NCBI GenInfo Identifier: | 50400598 |
NCBI Gene ID: | 10513 |
NCBI Accession: | Q92624.2 |
UniProt Secondary Accession: | Q92624,O95095, Q8WVC9, A8K862, |
UniProt Related Accession: | Q92624 |
Molecular Weight: | 66,853 Da |
NCBI Full Name: | Amyloid protein-binding protein 2 |
NCBI Synonym Full Names: | amyloid beta precursor protein binding protein 2 |
NCBI Official Symbol: | APPBP2 |
NCBI Official Synonym Symbols: | PAT1; APP-BP2; HS.84084 |
NCBI Protein Information: | amyloid protein-binding protein 2 |
UniProt Protein Name: | Amyloid protein-binding protein 2 |
UniProt Synonym Protein Names: | Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1 |
Protein Family: | Amyloid protein-binding protein |
UniProt Gene Name: | APPBP2 |
UniProt Entry Name: | APBP2_HUMAN |
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