Anti-APOBEC3D Antibody (CAB11648)
- SKU:
- CAB11648
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-APOBEC3D Antibody |
| 抗体コード: | CAB11648 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human APOBEC3D (NP_689639.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Raji, HepG2, 293T, Mouse spleen, Mouse liver, Mouse kidney, Rat liver, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human APOBEC3D (NP_689639.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AMYP HIFY FHFK NLLK ACGR NESW LCFT MEVT KHHS AVFR KRGV FRNQ VDPE THCH AERC FLSW FCDD ILSP NTNY EVTW YTSW SPCP ECAG EVAE FLAR HSNV NLTI FTAR LCYF WDTD YQEG LCSL SQEG ASVK IMGY KDFV SCWK NFVY SDDE PFKP WKGL QTNF RLLK RRLR EILQ |
| 遺伝子ID: | 140564 |
| Uniprot: | Q96AK3 |
| セルラーロケーション: | Cytoplasm, P-body |
| 計算された分子量: | 46kDa |
| 観察された分子量: | 43kDa |
| 同義語: | APOBEC3D, A3D, APOBEC3DE, APOBEC3E, ARP6 |
| バックグラウンド: | This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. |
| UniProt Protein Function: | APOBEC3D: Probable DNA cytidine deaminase involved in foreign DNA clearance. May provide cellular innate resistance to a specific panel of genetic invaders including endogenous retroelements and a subset of viruses. Belongs to the cytidine and deoxycytidylate deaminase family. |
| UniProt Protein Details: | Protein type:Hydrolase; EC 3.5.4.- Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: cytoplasm Molecular Function:zinc ion binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines Biological Process: negative regulation of retroviral genome replication; innate immune response; defense response to virus |
| UniProt Code: | Q96AK3 |
| NCBI GenInfo Identifier: | 48474596 |
| NCBI Gene ID: | |
| NCBI Accession: | Q96AK3.1 |
| UniProt Secondary Accession: | Q96AK3,Q5JZ91, Q7Z2N2, Q7Z2N5, Q7Z2N6, |
| Molecular Weight: | 46598 |
| NCBI Full Name: | DNA dC-> |
| UniProt Protein Name: | DNA dC->dU-editing enzyme APOBEC-3D |
| Protein Family: | DNA dC->dU-editing enzyme |
| UniProt Gene Name: | APOBEC3D |
| UniProt Entry Name: | ABC3D_HUMAN |
 | Western blot analysis of extracts of various cell lines, using APOBEC3D antibody (CAB11648) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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