Anti-APOBEC3C Antibody (CAB5877)
- SKU:
- CAB5877
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-APOBEC3C Antibody |
| 抗体コード: | CAB5877 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human APOBEC3C (NP_055323.2). |
| 申し込み: | IF |
| 推奨希釈: | IF 1:20 - 1:50 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human APOBEC3C (NP_055323.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MNPQ IRNP MKAM YPGT FYFQ FKNL WEAN DRNE TWLC FTVE GIKR RSVV SWKT GVFR NQVD SETH CHAE RCFL SWFC DDIL SPNT KYQV TWYT SWSP CPDC AGEV AEFL ARHS NVNL TIFT ARLY YFQY PCYQ EGLR SLSQ EGVA VEIM DYED FKYC WENF VYND NEPF KPWK GLKT NFRL LKRR LRES LQ |
| 遺伝子ID: | 27350 |
| Uniprot: | Q9NRW3 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 22kDa |
| 観察された分子量: |
| 同義語: | APOBEC3C, A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3 |
| バックグラウンド: | This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. |
| UniProt Protein Function: | APOBEC3C: Host cellular restriction factor that may have antiviral activities against exogenous and endogenous viruses, as well as retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. Belongs to the cytidine and deoxycytidylate deaminase family. |
| UniProt Protein Details: | Protein type:Hydrolase; EC 3.5.4.-; RNA-binding Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: cytoplasm; nucleus Molecular Function:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; protein binding; zinc ion binding Biological Process: cytidine deamination; defense response to virus; innate immune response; negative regulation of viral genome replication; viral reproduction |
| NCBI Summary: | This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NRW3 |
| NCBI GenInfo Identifier: | 48474983 |
| NCBI Gene ID: | 27350 |
| NCBI Accession: | Q9NRW3.2 |
| UniProt Secondary Accession: | Q9NRW3,Q5JZ92, Q7Z2N7, Q96F12, B2R884, |
| UniProt Related Accession: | Q9NRW3 |
| Molecular Weight: | 22,826 Da |
| NCBI Full Name: | DNA dC-> |
| NCBI Synonym Full Names: | apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C |
| NCBI Official Symbol: | APOBEC3C |
| NCBI Official Synonym Symbols: | A3C; PBI; ARP5; ARDC2; ARDC4; APOBEC1L; bK150C2.3 |
| NCBI Protein Information: | DNA dC->dU-editing enzyme APOBEC-3C |
| UniProt Protein Name: | DNA dC->dU-editing enzyme APOBEC-3C |
| UniProt Synonym Protein Names: | APOBEC1-like; Phorbolin I |
| Protein Family: | DNA dC->dU-editing enzyme |
| UniProt Gene Name: | APOBEC3C |
| UniProt Entry Name: | ABC3C_HUMAN |
 | Immunofluorescence analysis of U2OS cells using APOBEC3C antibody (CAB5877). Blue: DAPI for nuclear staining. |