Anti-AP1G2 Antibody (CAB17582)
- SKU:
- CAB17582
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-AP1G2 Antibody |
| 抗体コード: | CAB17582 |
| 抗体サイズ: | 20uL, 50 uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-360 of human AP1G2 (NP_001269404). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-360 of human AP1G2 (NP_001269404). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SLLR LVQS DHSA VQRH RPTV VECL RETD ASLS RRAL ELSL ALVN SSNV RAMM QELQ AFLE SCPP DLRA DCAS GILL AAER FAPT KRWH IDTI LHVL TTAG T |
| 遺伝子ID: | 8906 |
| Uniprot: | O75843 |
| セルラーロケーション: | |
| 計算された分子量: | 87kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | AP1G2, G2AD |
| バックグラウンド: | Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. Several alternatively spliced transcript variants of this gene exist, but their full-length nature is not known. [provided by RefSeq, Aug 2013] |
| UniProt Protein Function: | AP1G2: May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV). Belongs to the adaptor complexes large subunit family. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: AP-1 adaptor complex; Golgi apparatus; Golgi membrane; Golgi-associated vesicle; membrane; transport vesicle Molecular Function:protein binding |
| NCBI Summary: | Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. Several alternatively spliced transcript variants of this gene exist, but their full-length nature is not known. [provided by RefSeq, Aug 2013] |
| UniProt Code: | O75843 |
| NCBI GenInfo Identifier: | 12643299 |
| NCBI Gene ID: | 8906 |
| NCBI Accession: | O75843.1 |
| UniProt Secondary Accession: | O75843,O75504, D3DS51, |
| UniProt Related Accession: | O75843 |
| Molecular Weight: | 87,117 Da |
| NCBI Full Name: | AP-1 complex subunit gamma-like 2 |
| NCBI Synonym Full Names: | adaptor related protein complex 1 gamma 2 subunit |
| NCBI Official Symbol: | AP1G2 |
| NCBI Official Synonym Symbols: | G2AD |
| NCBI Protein Information: | AP-1 complex subunit gamma-like 2 |
| UniProt Protein Name: | AP-1 complex subunit gamma-like 2 |
| UniProt Synonym Protein Names: | Gamma2-adaptin; G2ad |
| Protein Family: | AP-1 complex |
| UniProt Gene Name: | AP1G2 |
| UniProt Entry Name: | AP1G2_HUMAN |