Anti-AP1B1 Antibody (CAB16304)
- SKU:
- CAB16304
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-AP1B1 Antibody |
| 抗体コード: | CAB16304 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AP1B1 (NP_001118.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, C6, Mouse liver |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AP1B1 (NP_001118.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SDLF DLTS GVGT LSGS YVAP KAVW LPAM KAKG LEIS GTFT RQVG SISM DLQL TNKA LQVM TDFA IQFN RNSF GLAP AAPL QVHA PLSP NQTV EISL PLST V |
| 遺伝子ID: | 162 |
| Uniprot: | Q10567 |
| セルラーロケーション: | |
| 計算された分子量: | 101kDa/103kDa/104kDa |
| 観察された分子量: | 105kDa |
| 同義語: | AP1B1, ADTB1, AP105A, BAM22, CLAPB2 |
| バックグラウンド: | Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| NCBI Summary: | Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q10567 |
| NCBI GenInfo Identifier: | 260436864 |
| NCBI Gene ID: | 162 |
| NCBI Accession: | NP_001159491.1 |
| UniProt Secondary Accession: | Q10567,P78436, Q20WL3, Q86X54, C9JRD1, F8WDL0, |
| UniProt Related Accession: | Q10567 |
| Molecular Weight: | 101,348 Da |
| NCBI Full Name: | AP-1 complex subunit beta-1 isoform c |
| NCBI Synonym Full Names: | adaptor related protein complex 1 subunit beta 1 |
| NCBI Official Symbol: | AP1B1 |
| NCBI Official Synonym Symbols: | ADTB1; BAM22; AP105A; CLAPB2 |
| NCBI Protein Information: | AP-1 complex subunit beta-1 |
| UniProt Protein Name: | AP-1 complex subunit beta-1 |
| UniProt Synonym Protein Names: | Adaptor protein complex AP-1 subunit beta-1; Adaptor-related protein complex 1 subunit beta-1; Beta-1-adaptin; Beta-adaptin 1; Clathrin assembly protein complex 1 beta large chain; Golgi adaptor HA1/AP1 adaptin beta subunit |
| Protein Family: | AP-1 complex |
| UniProt Gene Name: | AP1B1 |
 | Western blot analysis of extracts of various cell lines, using AP1B1 antibody (CAB16304) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5min. |
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