The Anti-ANPRB/NRP2 Antibody (CAB19255) is a highly specific tool for researchers studying ANPRB/NRP2, a cell surface receptor known to play a role in angiogenesis and axon guidance. This polyclonal antibody, produced in rabbits, has been rigorously validated for use in various applications, including Western blotting and immunohistochemistry.ANPRB/NRP2 is a critical factor in developmental processes and has been implicated in various disease states, including cancer and neurological disorders. By targeting the ANPRB/NRP2 protein, researchers can gain valuable insights into its function and potential therapeutic implications.
This antibody opens up new avenues for investigation in the fields of oncology, neuroscience, and vascular biology.With its high specificity and sensitivity, the Anti-ANPRB/NRP2 Antibody (CAB19255) is an essential tool for any researcher looking to deepen their understanding of ANPRB/NRP2 and its impact on human health. Harnessing the power of this antibody can lead to exciting discoveries and advancements in the fields of cancer research and neurobiology.
Product Name:
ANPRB/NRP2 Rabbit Monoclonal Antibody
SKU:
CAB19255
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594).
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
Purification Method:
Affinity purification
Gene ID:
4882
Clone Number:
ARC2421
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ANPRB/NRP2 Rabbit mAb (CAB19255) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
