Anti-ANLN Antibody (CAB6524)
- SKU:
- CAB6524
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-ANLN Antibody |
| 抗体コード: | CAB6524 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 845-1124 of human ANLN (NP_061155.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | 293T, MCF7 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 845-1124 of human ANLN (NP_061155.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ATPL ASTS NSLN GDAL TFTT TFTL QDVS NDFE INIE VYSL VQKK DPSG LDKK KKTS KSKA ITPK RLLT SITT KSNI HSSV MASP GGLS AVRT SNFA LVGS YTLS LSSV GNTK FVLD KVPF LSSL EGHI YLKI KCQV NSSV EERG FLTI FEDV SGFG AWHR RWCV LSGN CISY WTYP DDEK RKNP IGRI NLAN CTSR QIEP ANRE FCAR RNTF ELIT VRPQ REDD RETL VSQC RDTL CVTK NWLS ADTK EERD LWMQ KLNQ VLVD IRLW QPDA CYKP IGKP |
| 遺伝子ID: | 54443 |
| Uniprot: | Q9NQW6 |
| セルラーロケーション: | Cytoplasm, Nucleus, cell cortex, cytoskeleton |
| 計算された分子量: | 120kDa/124kDa |
| 観察された分子量: | 120kDa |
| 同義語: | ANLN, FSGS8, Scraps, scra, anillin |
| バックグラウンド: | This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | anillin: an actin binding protein that interacts with cleavage furrow proteins such as septins and may play a role in cytokinesis. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Actin-binding Chromosomal Location of Human Ortholog: 7p15-p14 Cellular Component: nucleoplasm; intracellular membrane-bound organelle; contractile ring; actin cytoskeleton Molecular Function:actin binding Biological Process: mitosis; cytokinesis after mitosis; septin ring assembly; regulation of exit from mitosis; hemopoietic progenitor cell differentiation Disease: Focal Segmental Glomerulosclerosis 8 |
| NCBI Summary: | This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q9NQW6 |
| NCBI GenInfo Identifier: | 90111962 |
| NCBI Gene ID: | 54443 |
| NCBI Accession: | Q9NQW6.2 |
| UniProt Secondary Accession: | Q9NQW6,Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0, |
| UniProt Related Accession: | Q9NQW6 |
| Molecular Weight: | 1124 |
| NCBI Full Name: | Actin-binding protein anillin |
| NCBI Synonym Full Names: | anillin, actin binding protein |
| NCBI Official Symbol: | ANLN |
| NCBI Official Synonym Symbols: | scra; FSGS8; Scraps |
| NCBI Protein Information: | actin-binding protein anillin |
| UniProt Protein Name: | Actin-binding protein anillin |
| Protein Family: | Anillin |
| UniProt Gene Name: | ANLN |
| UniProt Entry Name: | ANLN_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ANLN antibody (CAB6524) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of A549 cells using ANLN antibody (CAB6524). |
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