Anti-ANGPT4 Antibody (CAB10589)
- SKU:
- CAB10589
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-ANGPT4 Antibody |
| 抗体コード: | CAB10589 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-260 of human ANGPT4 (NP_057069.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-260 of human ANGPT4 (NP_057069.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TRQE ADRG CETL VVQH GHCS YTFL LPKS EPCP PGPE VSRD SNTL QRES LANP LHLG KLPT QQVK QLEQ ALQN NTQW LKKL ERAI KTIL RSKL EQVQ QQMA QNQT APML ELGT SLLN QTTA QIRK LTDM EAQL LNQT SRMD AQMP ETFL STNK LENQ LLLQ RQKL QQLQ GQNS ALEK RLQA LETK QQEE LASI LSKK AKLL NTLS RQSA ALTN IERG LRGV RHNS SLLQ DQQH SLRQ |
| 遺伝子ID: | 51378 |
| Uniprot: | Q9Y264 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 46kDa/56kDa |
| 観察された分子量: | 57kDa |
 | Western blot - ANGPT4 Polyclonal Antibody (CAB10589) |
| 同義語: | ANGPT4, ANG3, ANG4 |
| バックグラウンド: | Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. |
| UniProt Protein Function: | ANGPT4: Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 20p13 Cellular Component: extracellular space; extracellular region Molecular Function:transmembrane receptor protein tyrosine kinase activator activity; receptor tyrosine kinase binding Biological Process: positive regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of angiogenesis; transmembrane receptor protein tyrosine kinase activation (dimerization); endothelial cell proliferation; positive regulation of blood vessel endothelial cell migration; angiogenesis; negative regulation of blood vessel endothelial cell migration; blood coagulation; leukocyte migration; negative regulation of apoptosis |
| NCBI Summary: | Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y264 |
| NCBI GenInfo Identifier: | 7705276 |
| NCBI Gene ID: | 51378 |
| NCBI Accession: | NP_057069.1 |
| UniProt Secondary Accession: | Q9Y264,Q5TFF4, Q9H4Z4, |
| UniProt Related Accession: | Q9Y264 |
| Molecular Weight: | 56,849 Da |
| NCBI Full Name: | angiopoietin-4 |
| NCBI Synonym Full Names: | angiopoietin 4 |
| NCBI Official Symbol: | ANGPT4 |
| NCBI Official Synonym Symbols: | AGP4; ANG4; ANG-3 |
| NCBI Protein Information: | angiopoietin-4; ANG-4; angiopoietin-3; dJ824F16.2 (angiopoietin 4) |
| UniProt Protein Name: | Angiopoietin-4 |
| UniProt Synonym Protein Names: | Angiopoietin-3 |
| Protein Family: | Angiogenin |
| UniProt Gene Name: | ANGPT4 |
| UniProt Entry Name: | ANGP4_HUMAN |