Anti-ANAPC2 Antibody (CAB8066)
- SKU:
- CAB8066
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | ANAPC2 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8066 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human ANAPC2 (NP_037498.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brian, Mouse kidney, Rat brian, Rat kidney |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human ANAPC2 (NP_037498.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | YISA IKAL RVLD PSMV ILEV ACEP IRRY LRTR EDTV RQIV AGLT GDSD GTGD LAVE LSKT DPAS LETG QDSE DDSG EPED WVPD PVDA DPGK SSSK RRSS D |
| 遺伝子ID: | 29882 |
| Uniprot: | Q9UJX6 |
| セルラーロケーション: | |
| 計算された分子量: | 93kDa |
| 観察された分子量: | 102kDa |
| 同義語: | ANAPC2, APC2 |
| バックグラウンド: | A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. |
| NCBI Summary: | A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UJX6 |
| NCBI GenInfo Identifier: | 37537863 |
| NCBI Gene ID: | 29882 |
| NCBI Accession: | Q9UJX6.1 |
| UniProt Related Accession: | Q9UJX6 |
| Molecular Weight: | 93kDa |
| NCBI Full Name: | Anaphase-promoting complex subunit 2 |
| NCBI Synonym Full Names: | anaphase promoting complex subunit 2 |
| NCBI Official Symbol: | ANAPC2 |
| NCBI Official Synonym Symbols: | APC2 |
| NCBI Protein Information: | anaphase-promoting complex subunit 2 |
| UniProt Protein Name: | Anaphase-promoting complex subunit 2 |
| UniProt Synonym Protein Names: | Cyclosome subunit 2 |
| Protein Family: | Anaphase-promoting complex |
| UniProt Gene Name: | ANAPC2 |
| UniProt Entry Name: | ANC2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ANAPC2 antibody (CAB8066) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |