Anti-alpha 1 Antichymotrypsin Antibody (CAB11364)
- SKU:
- CAB11364
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-alpha 1 Antichymotrypsin Antibody |
抗体コード: | CAB11364 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human alpha 1 Antichymotrypsin |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | Human plasma, Mouse liver |
免疫原: | A synthesized peptide derived from human alpha 1 Antichymotrypsin |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 12 |
Uniprot: | P01011 |
セルラーロケーション: | |
計算された分子量: | 50-70kDa |
観察された分子量: | 66KDa |
同義語: | AACT, ACT, GIG24, GIG25 |
バックグラウンド: | The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | SERPINA3: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 14q32.1 Cellular Component: extracellular space; extracellular region; intracellular; nucleus Molecular Function:serine-type endopeptidase inhibitor activity; protein binding; DNA binding Biological Process: regulation of lipid metabolic process; maintenance of gastrointestinal epithelium; acute-phase response; inflammatory response |
NCBI Summary: | The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008] |
UniProt Code: | P01011 |
NCBI GenInfo Identifier: | 112874 |
NCBI Gene ID: | 12 |
NCBI Accession: | P01011.2 |
UniProt Related Accession: | P01011 |
Molecular Weight: | |
NCBI Full Name: | Alpha-1-antichymotrypsin |
NCBI Synonym Full Names: | serpin family A member 3 |
NCBI Official Symbol: | SERPINA3 |
NCBI Official Synonym Symbols: | ACT; AACT; GIG24; GIG25 |
NCBI Protein Information: | alpha-1-antichymotrypsin |
UniProt Protein Name: | Alpha-1-antichymotrypsin |
UniProt Synonym Protein Names: | Cell growth-inhibiting gene 24/25 protein; Serpin A3Alpha-1-antichymotrypsin His-Pro-less |
Protein Family: | Agmatine coumaroyltransferase |
UniProt Gene Name: | SERPINA3 |
UniProt Entry Name: | AACT_HUMAN |