Anti-ALKBH5 Antibody (CAB11684)
- SKU:
- CAB11684
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| 抗体名: | Anti-ALKBH5 Antibody |
| 抗体コード: | CAB11684 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 245-394 of human ALKBH5 (NP_060228.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, Mouse testis, Rat spleen, Rat lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 245-394 of human ALKBH5 (NP_060228.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SLPV RRGS VTVL SGYA ADEI THCI RPQD IKER RAVI ILRK TRLD APRL ETKS LSSS VLPP SYAS DRLS GNNR DPAL KPKR SHRK ADPD AAHR PRIL EMDK EENR RSVL LPTH RRRG SFSS ENYW RKSY ESSE DCSE AAGS PARK VKMR RH |
| 遺伝子ID: | 54890 |
| Uniprot: | Q6P6C2 |
| セルラーロケーション: | Nucleus speckle |
| 計算された分子量: | 43kDa/44kDa/52kDa |
| 観察された分子量: | 40-52KDa |
| 同義語: | ALKBH5, ABH5, OFOXD, OFOXD1 |
| バックグラウンド: |
| UniProt Protein Function: | ALKBH5: a protein contaning a 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily domain. May be involved in DNA alkylation damage repair |
| UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.14.11.-; DNA repair, damage; RNA-binding; Membrane protein, integral Chromosomal Location of Human Ortholog: 17p11.2|17p11.2 Cellular Component: nuclear speck; nucleus Molecular Function:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Biological Process: mRNA export from nucleus; mRNA processing; positive regulation of defense response to virus by host; response to hypoxia; spermatogenesis |
| UniProt Code: | Q6P6C2 |
| NCBI GenInfo Identifier: | 408359959 |
| NCBI Gene ID: | 54890 |
| NCBI Accession: | Q6P6C2.2 |
| UniProt Secondary Accession: | Q6P6C2,Q9NXD6, B4DVJ4, D3DXC6, |
| UniProt Related Accession: | Q6P6C2 |
| Molecular Weight: | 43,049 Da |
| NCBI Full Name: | RNA demethylase ALKBH5 |
| NCBI Synonym Full Names: | alkB homolog 5, RNA demethylase |
| NCBI Official Symbol: | ALKBH5 |
| NCBI Official Synonym Symbols: | ABH5; OFOXD; OFOXD1 |
| NCBI Protein Information: | RNA demethylase ALKBH5 |
| UniProt Protein Name: | RNA demethylase ALKBH5 |
| UniProt Synonym Protein Names: | Alkylated DNA repair protein alkB homolog 5; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 |
| Protein Family: | RNA demethylase |
| UniProt Gene Name: | ALKBH5 |
| UniProt Entry Name: | ALKB5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ALKBH5 antibody (CAB11684) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Western blot analysis of extracts of various cell lines, using ALKBH5 antibody (CAB11684) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |