Anti-ALDH1A1 Antibody (CAB0157)
- SKU:
- CAB0157
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ALDH1A1 Antibody |
| 抗体コード: | CAB0157 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human ALDH1A1 |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, A-549, K-562, Mouse lung, Mouse testis, Rat lung, Rat liver, Rat kidney |
| 免疫原: | A synthesized peptide derived from human ALDH1A1 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 216 |
| Uniprot: | P00352 |
| セルラーロケーション: | |
| 計算された分子量: | 55kDa |
| 観察された分子量: | 55KDa |
 | Western blot - ALDH1A1 Rabbit mAb (CAB0157) |
| 同義語: | ALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1 |
| バックグラウンド: | The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011] |
| UniProt Protein Function: | ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. |
| UniProt Protein Details: | Protein type:GAPs, Ras; EC 1.2.1.36; GAPs; Cofactor and Vitamin Metabolism - retinol; Apoptosis; Oxidoreductase Chromosomal Location of Human Ortholog: 9q21.13 Cellular Component: cytoplasm; cytosol Molecular Function:aldehyde dehydrogenase (NAD) activity; androgen binding; 3-chloroallyl aldehyde dehydrogenase activity; benzaldehyde dehydrogenase (NAD+) activity; retinal dehydrogenase activity Biological Process: retinol metabolic process; xenobiotic metabolic process; aldehyde metabolic process; ethanol oxidation |
| NCBI Summary: | The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011] |
| UniProt Code: | P00352 |
| NCBI GenInfo Identifier: | 118495 |
| NCBI Gene ID: | 216 |
| NCBI Accession: | P00352.2 |
| UniProt Related Accession: | P00352 |
| Molecular Weight: | ~ 50-55kDa |
| NCBI Full Name: | Retinal dehydrogenase 1 |
| NCBI Synonym Full Names: | aldehyde dehydrogenase 1 family member A1 |
| NCBI Official Symbol: | ALDH1A1 |
| NCBI Official Synonym Symbols: | ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e |
| NCBI Protein Information: | retinal dehydrogenase 1 |
| UniProt Protein Name: | Retinal dehydrogenase 1 |
| UniProt Synonym Protein Names: | ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic |
| Protein Family: | Retinal dehydrogenase |
| UniProt Gene Name: | ALDH1A1 |
| UniProt Entry Name: | AL1A1_HUMAN |