Anti-ADRM1 Antibody (CAB4481)
- SKU:
- CAB4481
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ADRM1
- Synonyms:
- ARM-1
- Synonyms:
- ARM1
- Synonyms:
- GP110
Frequently bought together:
Description
| 抗体名: | ADRM1 Rabbit pAb |
| 抗体コード: | CAB4481 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | ADRM1, ARM-1, ARM1, GP110 |
| 申し込み: | WB, IHC, IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 108-407 of human ADRM1 (NP_008933.2). |
| 申し込み: | WB, IHC, IF |
| 推奨される希釈: | WB 1:1000 - 1:4000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, LO2, 293T, MCF7, SW480 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 108-407 of human ADRM1 (NP_008933.2). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | WMQE PKTD QDEE HCRK VNEY LNNP PMPG ALGA SGSS GHEL SALG GEGG LQSL LGNM SHSQ LMQL IGPA GLGG LGGL GALT GPGL ASLL GSSG PPGS SSSS SSRS QSAA VTPS STTS STRA TPAP SAPA AASA TSPS PAPS SGNG ASTA ASPT QPIQ LSDL QSIL ATMN VPAG PAGG QQVD LASV LTPE IMAP ILAN ADVQ ERLL PYLP SGES LPQT ADEI QNTL TSPQ FQQA LGMF SAAL ASGQ LGPL MCQF GLPA EAVE AANK GDVE AFAK AMQN NAKP EQKE GDTK DKKD EEED MSLD |
| 遺伝子ID: | 11047 |
| Uniprot: | Q16186 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 42kDa |
| 観察された分子量: | 42kDa |
| UniProt Protein Function: | ADRM1: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family. |
| UniProt Protein Details: | Protein type:Proteasome complex; Cell development/differentiation Chromosomal Location of Human Ortholog: 20q13.33 Cellular Component: proteasome complex; nucleoplasm; membrane; integral to plasma membrane; cytoplasm; plasma membrane Molecular Function:protein binding; protease binding Biological Process: RNA elongation from RNA polymerase II promoter; proteasome assembly |
| NCBI Summary: | This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q16186 |
| NCBI GenInfo Identifier: | 20141265 |
| NCBI Gene ID: | 11047 |
| NCBI Accession: | Q16186.2 |
| UniProt Related Accession: | Q16186 |
| Molecular Weight: | |
| NCBI Full Name: | Proteasomal ubiquitin receptor ADRM1 |
| NCBI Synonym Full Names: | adhesion regulating molecule 1 |
| NCBI Official Symbol: | ADRM1 |
| NCBI Official Synonym Symbols: | ARM1; ARM-1; GP110 |
| NCBI Protein Information: | proteasomal ubiquitin receptor ADRM1 |
| UniProt Protein Name: | Proteasomal ubiquitin receptor ADRM1 |
| UniProt Synonym Protein Names: | 110 kDa cell membrane glycoprotein; Gp110; Adhesion-regulating molecule 1; ARM-1; Proteasome regulatory particle non-ATPase 13; hRpn13; Rpn13 homolog |
| UniProt Gene Name: | ADRM1 |
| UniProt Entry Name: | ADRM1_HUMAN |