Anti-ADPRM Antibody (CAB12883)

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SKU:
CAB12883
Product type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

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抗体名:Anti-ADPRM Antibody
抗体コード:CAB12883
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_064618.3).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Mouse, Rat
ポジティブサンプル:Mouse lung, Mouse spleen, Rat brain, Rat lung
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_064618.3).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:SEPQ FVQF NGGF SQEQ LNWL NEVL TFSD TNQE KVVI VSHL PIYP DASD NVCL AWNY RDAL AVIW SHEC VVCF FAGH THDG GYSE DPFG VYHV NLEG VIET APDS QAFG TVHV YPDK MMLK GRGR VPDR IMNY KKER AFHC
遺伝子ID:56985
Uniprot:Q3LIE5
セルラーロケーション:
計算された分子量:24kDa/39kDa
観察された分子量:39kDa
同義語:ADPRM, C17orf48, MDS006, NBLA03831
バックグラウンド:
UniProt Protein Function:ADPRM: Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP- choline and CDP-ethanolamine, but not other non-reducing ADP- sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress. Belongs to the ADPRibase-Mn family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.6.1.13; EC 3.6.1.16; EC 3.6.1.53; Hydrolase

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: cytosol

Molecular Function:ADP-ribose diphosphatase activity

UniProt Code:Q3LIE5
NCBI GenInfo Identifier:121942723
NCBI Gene ID:56985
NCBI Accession:Q3LIE5.1
UniProt Secondary Accession:Q3LIE5,Q9BVD4, Q9NRU8, A8K9B4, D3DTS4,
UniProt Related Accession:Q3LIE5
Molecular Weight:40kDa
NCBI Full Name:Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
NCBI Synonym Full Names:ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
NCBI Official Symbol:ADPRM  
NCBI Official Synonym Symbols:MDS006; C17orf48; NBLA03831  
NCBI Protein Information:manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
UniProt Protein Name:Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
UniProt Synonym Protein Names:ADPRibase-Mn; CDP-choline phosphohydrolase
UniProt Gene Name:ADPRM  
Anti-ADPRM Antibody (CAB12883)Western blot analysis of extracts of various cell lines, using ADPRM antibody (CAB12883) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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