Anti-ADPRH Antibody (CAB6277)
- SKU:
- CAB6277
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ADPRH Antibody |
| 抗体コード: | CAB6277 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-270 of human ADPRH (NP_001116.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | K-562, SW480, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-270 of human ADPRH (NP_001116.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AYAV NSRP PLQW GKGL MELL PEAK KYIV QSGY FVEE NLQH WSYF QTKW ENYL KLRG ILDG ESAP TFPE SFGV KERD QFYT SLSY SGWG GSS |
| 遺伝子ID: | 141 |
| Uniprot: | P54922 |
| セルラーロケーション: | |
| 計算された分子量: | 39kDa |
| 観察された分子量: | 39kDa |
| 同義語: | ADPRH, ARH1 |
| バックグラウンド: | The enzyme encoded by this gene catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes that require DTT for maximal activity, the human enzyme is DTT-independent. Alternatively spliced transcript variants that encode different protein isoforms have been described. |
| UniProt Protein Function: | ADPRH: Catalyzes the reverse reaction of mono-ADP-ribosylation. Belongs to the ADP-ribosylglycohydrolase family. |
| UniProt Protein Details: | Protein type:Hydrolase; EC 3.2.2.19 Chromosomal Location of Human Ortholog: 3q13.31-q13.33 Molecular Function:ADP-ribosylarginine hydrolase activity; magnesium ion binding Biological Process: protein amino acid de-ADP-ribosylation; protein modification process |
| NCBI Summary: | The enzyme encoded by this gene catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes that require DTT for maximal activity, the human enzyme is DTT-independent. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, May 2014] |
| UniProt Code: | P54922 |
| NCBI GenInfo Identifier: | 1703392 |
| NCBI Gene ID: | 141 |
| NCBI Accession: | P54922.1 |
| UniProt Secondary Accession: | P54922,B2R8H1, D3DN83, |
| UniProt Related Accession: | P54922 |
| Molecular Weight: | 357 |
| NCBI Full Name: | [Protein ADP-ribosylarginine] hydrolase |
| NCBI Synonym Full Names: | ADP-ribosylarginine hydrolase |
| NCBI Official Symbol: | ADPRH |
| NCBI Official Synonym Symbols: | ARH1 |
| NCBI Protein Information: | ADP-ribosylarginine hydrolase; ADP-ribose-L-arginine cleaving enzyme |
| UniProt Protein Name: | [Protein ADP-ribosylarginine] hydrolase |
| UniProt Synonym Protein Names: | ADP-ribose-L-arginine cleaving enzyme |
| Protein Family: | [Protein ADP-ribosylarginine] hydrolase |
| UniProt Gene Name: | ADPRH |
| UniProt Entry Name: | ADPRH_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ADPRH antibody (CAB6277) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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