Anti-ADCY6 Antibody (CAB20431)

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SKU:
CAB20431
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
AC6
Synonyms:
LCCS8
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Description

抗体名:ADCY6 Rabbit pAb
抗体コード:CAB20431
サイズ:50uL, 100uL
同義語:AC6, LCCS8
申し込み:WB
反応性:Human
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ADCY6 (NP_056085.1).
申し込み:WB
推奨される希釈:WB 1:500 - 1:2000
反応性:Human
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ADCY6 (NP_056085.1).
精製方法:Affinity purification
保管所:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:112
Uniprot:O43306
計算された分子量:130kDa
観察された分子量:Refer to figures
UniProt Protein Function:ADCY6: a membrane-associated enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Expressed in normal thyroid and brain tissues, as well as some tumors; its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants. Protein type: Nucleotide Metabolism - purine; EC 4.6.1.1; Transporter; Lyase; Adenylyl cyclase; Membrane protein, multi-pass; Transporter, aquaporin family; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q12-q13 Cellular Component: membrane; plasma membrane; integral to membrane; cilium Molecular Function: protein binding; metal ion binding; protein kinase binding; ATP binding; adenylate cyclase activity Biological Process: epidermal growth factor receptor signaling pathway; synaptic transmission; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; phospholipase C activation; water transport; activation of protein kinase A; dopamine receptor signaling pathway; energy reserve metabolic process; innate immune response; renal water homeostasis; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; transmembrane transport; G-protein signaling, adenylate cyclase activating pathway Disease: Lethal Congenital Contracture Syndrome 8
UniProt Protein Details:
NCBI Summary:This gene encodes adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008]
UniProt Code:O43306
NCBI GenInfo Identifier:12644065
NCBI Gene ID:112
NCBI Accession:O43306.2
UniProt Secondary Accession:O43306,Q9NR75, Q9UDB0
UniProt Related Accession:O43306
Molecular Weight:
NCBI Full Name:Adenylate cyclase type 6
NCBI Synonym Full Names:adenylate cyclase 6
NCBI Official Symbol:ADCY6  
NCBI Official Synonym Symbols:AC6  
NCBI Protein Information:adenylate cyclase type 6; ATP pyrophosphate-lyase 6; adenylate cyclase type VI; adenylyl cyclase 6; ca(2+)-inhibitable adenylyl cyclase
UniProt Protein Name:Adenylate cyclase type 6
UniProt Synonym Protein Names:ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitable adenylyl cyclase
Protein Family:Adenylate cyclase
UniProt Gene Name:ADCY6  
UniProt Entry Name:ADCY6_HUMAN
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