Anti-ADAM28 Antibody (CAB14849)
- SKU:
- CAB14849
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ADAM28 Antibody |
| 抗体コード: | CAB14849 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 199-440 of human ADAM28 (NP_055080.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | SGC-7901, HT-29, THP-1, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 199-440 of human ADAM28 (NP_055080.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VQEH EKYI EYYL VLDN GEFK RYNE NQDE IRKR VFEM ANYV NMLY KKLN THVA LVGM EIWT DKDK IKIT PNAS FTLE NFSK WRGS VLSR RKRH DIAQ LITA TELA GTTV GLAF MSTM CSPY SVGV VQDH SDNL LRVA GTMA HEMG HNFG MFHD DYSC KCPS TICV MDKA LSFY IPTD FSSC SRLS YDKF FEDK LSNC LFNA PLPT DIIS TPIC GNQL VEMG EDCD CGTS EECT NICC DAKT CK |
| 遺伝子ID: | 10863 |
| Uniprot: | Q9UKQ2 |
| セルラーロケーション: | Cell membrane, Secreted, Single-pass type I membrane protein |
| 計算された分子量: | 61kDa/87kDa |
| 観察された分子量: | 87kDa |
| 同義語: | ADAM28, ADAM 28, MDC-L, MDCL, eMDC II, eMDCII |
| バックグラウンド: | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | ADAM28: May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.24.-; Membrane protein, integral; Motility/polarity/chemotaxis; Protease Chromosomal Location of Human Ortholog: 8p21.2 Molecular Function:metallopeptidase activity Biological Process: spermatogenesis |
| NCBI Summary: | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| UniProt Code: | Q9UKQ2 |
| NCBI GenInfo Identifier: | 748983380 |
| NCBI Gene ID: | 10863 |
| NCBI Accession: | NP_001291280.1 |
| UniProt Related Accession: | Q9UKQ2 |
| Molecular Weight: | |
| NCBI Full Name: | disintegrin and metalloproteinase domain-containing protein 28 isoform 4 preproprotein |
| NCBI Synonym Full Names: | ADAM metallopeptidase domain 28 |
| NCBI Official Symbol: | ADAM28 |
| NCBI Official Synonym Symbols: | MDCL; MDC-L; eMDCII; ADAM 28; eMDC II |
| NCBI Protein Information: | disintegrin and metalloproteinase domain-containing protein 28 |
| UniProt Protein Name: | Disintegrin and metalloproteinase domain-containing protein 28 |
| UniProt Synonym Protein Names: | Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; eMDC II; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; MDC-L |
| UniProt Gene Name: | ADAM28 |
 | Western blot analysis of extracts of various cell lines, using ADAM28 Rabbit pAb (CAB14849) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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