Anti-ADAM23 Antibody (CAB14263)
- SKU:
- CAB14263
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-ADAM23 Antibody |
抗体コード: | CAB14263 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human ADAM23 (NP_003803.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, Raji, Mouse heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human ADAM23 (NP_003803.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | VETW TEKD QIDI TTNP VQML HEFS KYRQ RIKQ HADA VHLI SRVT FHYK RSSL SYFG GVCS RTRG VGVN EYGL PMAV AQVL SQSL AQNL GIQW EPSS RKPK CDCT ESWG GCIM EETG VSHS RKFS KCSI LEYR DFLQ RGGG ACLF NRPT KLF |
遺伝子ID: | 8745 |
Uniprot: | O75077 |
セルラーロケーション: | Cell membrane, Secreted, Single-pass type I membrane protein |
計算された分子量: | 91kDa/92kDa |
観察された分子量: | 92kDa |
同義語: | ADAM23, MDC-3, MDC3 |
バックグラウンド: | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. |
UniProt Protein Function: | ADAM23: May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion Chromosomal Location of Human Ortholog: 2q33 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:integrin binding; metallopeptidase activity; protein binding Biological Process: central nervous system development |
NCBI Summary: | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013] |
UniProt Code: | O75077 |
NCBI GenInfo Identifier: | 56404446 |
NCBI Gene ID: | 8745 |
NCBI Accession: | O75077.1 |
UniProt Secondary Accession: | O75077,A2RU59, |
UniProt Related Accession: | O75077 |
Molecular Weight: | 92,130 Da |
NCBI Full Name: | Disintegrin and metalloproteinase domain-containing protein 23 |
NCBI Synonym Full Names: | ADAM metallopeptidase domain 23 |
NCBI Official Symbol: | ADAM23 |
NCBI Official Synonym Symbols: | MDC3; MDC-3 |
NCBI Protein Information: | disintegrin and metalloproteinase domain-containing protein 23 |
UniProt Protein Name: | Disintegrin and metalloproteinase domain-containing protein 23 |
UniProt Synonym Protein Names: | Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3; MDC-3 |
Protein Family: | Disintegrin and metalloproteinase domain-containing protein |
UniProt Gene Name: | ADAM23 |
UniProt Entry Name: | ADA23_HUMAN |
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