Anti-ACTR3B Antibody (CAB7824)
- SKU:
- CAB7824
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ACTR3B Antibody |
| 抗体コード: | CAB7824 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 189-418 of human ACTR3B (NP_065178.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, NCI-H125, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 189-418 of human ACTR3B (NP_065178.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CIKH IPIA GRDI TYFI QQLL RERE VGIP PEQS LETA KAIK EKYC YICP DIVK EFAK YDVD PRKW IKQY TGIN AINQ KKFV IDVG YERF LGPE IFFH PEFA NPDF MESI SDVV DEVI QNCP IDVR RPLY KNVV LSGG STMF RDFG RRLQ RDLK RVVD ARLR LSEE LSGG RIKP KPVE VQVV THHM QRYA VWFG GSML ASTP EFFQ VCHT KKDY EEYG PSIC RHNP VFGV MS |
| 遺伝子ID: | 57180 |
| Uniprot: | Q9P1U1 |
| セルラーロケーション: | Cell projection, Cytoplasm, cytoskeleton |
| 計算された分子量: | 37kDa/39kDa/47kDa |
| 観察された分子量: | 48kDa |
| 同義語: | ACTR3B, ARP11, ARP3BETA |
| バックグラウンド: | This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. |
| UniProt Protein Function: | ACTR3B: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. Belongs to the actin family. ARP3 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 7q36.1 Cellular Component: Arp2/3 protein complex; cell projection; cytoplasm Molecular Function:actin binding; ATP binding |
| NCBI Summary: | This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q9P1U1 |
| NCBI GenInfo Identifier: | 74753111 |
| NCBI Gene ID: | 57180 |
| NCBI Accession: | Q9P1U1.1 |
| UniProt Secondary Accession: | Q9P1U1,Q7Z526, Q96BT2, A8MTG1, B4DFW4, |
| UniProt Related Accession: | Q9P1U1 |
| Molecular Weight: | 418 |
| NCBI Full Name: | Actin-related protein 3B |
| NCBI Synonym Full Names: | ARP3 actin-related protein 3 homolog B (yeast) |
| NCBI Official Symbol: | ACTR3B |
| NCBI Official Synonym Symbols: | ARP11; ARP3BETA |
| NCBI Protein Information: | actin-related protein 3B; ARP3-beta; actin-like protein 3B; actin-related protein ARP4; actin-related protein Arp11; actin-related protein 3-beta |
| UniProt Protein Name: | Actin-related protein 3B |
| UniProt Synonym Protein Names: | ARP3-beta; Actin-like protein 3B; Actin-related protein ARP4 |
| Protein Family: | Actin-related protein |
| UniProt Gene Name: | ACTR3B |
| UniProt Entry Name: | ARP3B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ACTR3B antibody (CAB7824) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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