Anti-ACTR1B Antibody (CAB15773)
- SKU:
- CAB15773
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ACTR1B Antibody |
| 抗体コード: | CAB15773 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human ACTR1B (NP_005726.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse thymus, Mouse brain, Mouse heart, Rat lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human ACTR1B (NP_005726.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MESY DIIA NQPV VIDN GSGV IKAG FAGD QIPK YCFP NYVG RPKH MRVM AGAL EGDL FIGP KAEE HRGL LTIR YPME HGVV RDWN DMER IWQY VYSK DQLQ TFSE E |
| 遺伝子ID: | 10120 |
| Uniprot: | P42025 |
| セルラーロケーション: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center |
| 計算された分子量: | 42kDa |
| 観察された分子量: | 42kDa |
| 同義語: | ACTR1B, ARP1B, CTRN2, PC3 |
| バックグラウンド: | This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. |
| UniProt Protein Function: | ACTR1B: Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. Belongs to the actin family. ARP1 subfamily. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 2q11.2 Cellular Component: centrosome; dynactin complex; membrane; cytoplasm; cytosol Molecular Function:protein binding; ATP binding Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II |
| NCBI Summary: | This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008] |
| UniProt Code: | P42025 |
| NCBI GenInfo Identifier: | 11342680 |
| NCBI Gene ID: | 10120 |
| NCBI Accession: | NP_005726.1 |
| UniProt Secondary Accession: | P42025,Q53SK5, Q9BRB7, D3DVH2, |
| UniProt Related Accession: | P42025 |
| Molecular Weight: | 42,293 Da |
| NCBI Full Name: | beta-centractin |
| NCBI Synonym Full Names: | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| NCBI Official Symbol: | ACTR1B |
| NCBI Official Synonym Symbols: | PC3; ARP1B; CTRN2 |
| NCBI Protein Information: | beta-centractin; centractin beta; actin-related protein 1B |
| UniProt Protein Name: | Beta-centractin |
| UniProt Synonym Protein Names: | Actin-related protein 1B; ARP1B |
| Protein Family: | Beta-centractin |
| UniProt Gene Name: | ACTR1B |
| UniProt Entry Name: | ACTY_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ACTR1B Rabbit pAb (CAB15773) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
 | Immunohistochemistry of paraffin-embedded Mouse kidney using ACTR1B Rabbit pAb (CAB15773) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Rat testis using ACTR1B Rabbit pAb (CAB15773) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Human colon carcinoma using ACTR1B Rabbit pAb (CAB15773) at dilution of 1:100 (40x lens). |
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