Anti-ACP1 Antibody (CAB15020)
- SKU:
- CAB15020
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ACP1 Antibody |
| 抗体コード: | CAB15020 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-144 of human ACP1 (NP_004291.1). |
| 申し込み: | IF |
| 推奨希釈: | IF 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-144 of human ACP1 (NP_004291.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GNIC RSPI AEAV FRKL VTDQ NISE NWRV DSAA TSGY EIGN PPDY RGQS CMKR HGIP MSHV ARQI TKED FATF DYIL CMDE SNLR DLNR KSNQ VKTC KAKI ELLG SYDP QKQL IIED PYYG NDSD FETV YQ |
| 遺伝子ID: | 52 |
| Uniprot: | P24666 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 12kDa/14kDa/17kDa/18kDa |
| 観察された分子量: |
| 同義語: | ACP1, HAAP, LMW-PTP, LMWPTP |
| バックグラウンド: | The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
| UniProt Protein Function: | ACP1: a phosphotyrosine protein phosphatase. Functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. Hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. Genetically polymorphic with three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene. |
| UniProt Protein Details: | Protein type:Cofactor and Vitamin Metabolism - riboflavin; EC 3.1.3.2; Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.48; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 2p25 Cellular Component: internal side of plasma membrane; cytoplasm Molecular Function:protein binding; acid phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity |
| NCBI Summary: | The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008] |
| UniProt Code: | P24666 |
| NCBI GenInfo Identifier: | 1709543 |
| NCBI Gene ID: | 52 |
| NCBI Accession: | P24666.3 |
| UniProt Related Accession: | P24666 |
| Molecular Weight: | Molecular Mass: 19.04kDaActual Protein Molecular Mass: 18kDa |
| NCBI Full Name: | Low molecular weight phosphotyrosine protein phosphatase |
| NCBI Synonym Full Names: | acid phosphatase 1 |
| NCBI Official Symbol: | ACP1 |
| NCBI Official Synonym Symbols: | HAAP; LMWPTP; LMW-PTP |
| NCBI Protein Information: | low molecular weight phosphotyrosine protein phosphatase |
| UniProt Protein Name: | Low molecular weight phosphotyrosine protein phosphatase |
| UniProt Synonym Protein Names: | Adipocyte acid phosphatase; Low molecular weight cytosolic acid phosphatase (EC:3.1.3.2); Red cell acid phosphatase 1 |
| Protein Family: | Low molecular weight phosphotyrosine protein phosphatase |
| UniProt Gene Name: | ACP1 |
| UniProt Entry Name: | PPAC_HUMAN |
 | Immunofluorescence analysis of HeLa cells using ACP1 antibody (CAB15020) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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