Anti-ABCG4 Antibody (CAB14596)
- SKU:
- CAB14596
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-ABCG4 Antibody |
| 抗体コード: | CAB14596 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-370 of human ABCG4 (NP_071452.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, A-549, U-937, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-370 of human ABCG4 (NP_071452.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KLYI LSQG QCIF KGVV TNLI PYLK GLGL HCPT YHNP ADFI IEVA SGEY GDLN PMLF RAVQ NGLC AMAE KKSS PEKN EVPA PCPP CPPE VDPI ESHT FATS T |
| 遺伝子ID: | 64137 |
| Uniprot: | Q9H172 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 60kDa/64kDa/65kDa/71kDa |
| 観察された分子量: | 72kDa |
| 同義語: | ABCG4, WHITE2 |
| バックグラウンド: | The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein is a member of the White subfamily and plays an important role in cellular cholesterol homeostasis. This protein functions as either a homodimer or as a heterodimer with another ABC subfamily protein such as ABCG1. |
| UniProt Protein Function: | ABCG4: May be involved in macrophage lipid homeostasis. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, ABC family Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: integral to membrane; plasma membrane Molecular Function:protein binding; protein homodimerization activity; protein heterodimerization activity; cholesterol transporter activity; ATPase activity; ATP binding Biological Process: metabolic process; cholesterol efflux; transmembrane transport |
| NCBI Summary: | The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H172 |
| NCBI GenInfo Identifier: | 17432915 |
| NCBI Gene ID: | 64137 |
| NCBI Accession: | Q9H172.2 |
| UniProt Secondary Accession: | Q9H172,Q8WWH0, Q8WWH1, Q8WWH2, A8K1B5, |
| UniProt Related Accession: | Q9H172 |
| Molecular Weight: | 646 |
| NCBI Full Name: | ATP-binding cassette sub-family G member 4 |
| NCBI Synonym Full Names: | ATP-binding cassette, sub-family G (WHITE), member 4 |
| NCBI Official Symbol: | ABCG4 |
| NCBI Official Synonym Symbols: | WHITE2 |
| NCBI Protein Information: | ATP-binding cassette sub-family G member 4; putative ABC transporter; ATP-binding cassette, subfamily G, member 4 |
| UniProt Protein Name: | ATP-binding cassette sub-family G member 4 |
| Protein Family: | ABC transporter G family |
| UniProt Gene Name: | ABCG4 |
| UniProt Entry Name: | ABCG4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ABCG4 antibody (CAB14596) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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