ALKBH4 Antibody, FITC conjugated (PACO48164)
- SKU:
- PACO48164
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | ALKBH4 Antibody, FITC conjugated (PACO48164) |
抗体コード: | PACO48164 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 protein (1-115AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation. |
シノニム: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (EC 1.14.11) (Alkylated DNA repair protein alkB homolog 4), ALKBH4, ABH4 |
UniProt Protein Function: | ALKBH4: Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron. Belongs to the alkB family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 1.14.11.- Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: cytoplasm; midbody; nucleus Molecular Function:metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; actin binding; demethylase activity Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; actomyosin structure organization and biogenesis; protein amino acid demethylation |
UniProt Code: | Q9NXW9 |
NCBI GenInfo Identifier: | 74734701 |
NCBI Gene ID: | 54784 |
NCBI Accession: | Q9NXW9.1 |
UniProt Related Accession: | Q9NXW9 |
Molecular Weight: | |
NCBI Full Name: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 |
NCBI Synonym Full Names: | alkB homolog 4, lysine demethylase |
NCBI Official Symbol: | ALKBH4 |
NCBI Official Synonym Symbols: | ABH4 |
NCBI Protein Information: | alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 |
UniProt Protein Name: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 |
UniProt Synonym Protein Names: | Alkylated DNA repair protein alkB homolog 4 |
UniProt Gene Name: | ALKBH4 |
UniProt Entry Name: | ALKB4_HUMAN |