ALDH3B1 Antibody, FITC conjugated (PACO53000)
- SKU:
- PACO53000
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | ALDH3B1 Antibody, FITC conjugated (PACO53000) |
抗体コード: | PACO53000 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Aldehyde dehydrogenase family 3 member B1 protein (168-449AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation. |
シノニム: | Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7), ALDH3B1, ALDH7 |
UniProt Protein Function: | ALDH3B1: Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Oxidoreductase; Amino Acid Metabolism - histidine; Amino Acid Metabolism - tyrosine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - phenylalanine; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.2.1.5; Carbohydrate Metabolism - glycolysis and gluconeogenesis Chromosomal Location of Human Ortholog: 11q13 Cellular Component: cytoplasm; plasma membrane; vesicle Molecular Function:3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; protein binding Biological Process: alcohol metabolic process; aldehyde catabolic process; lipid metabolic process; sphingolipid biosynthetic process |
NCBI Summary: | This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
UniProt Code: | P43353 |
NCBI GenInfo Identifier: | 1169285 |
NCBI Gene ID: | 221 |
NCBI Accession: | P43353.1 |
UniProt Secondary Accession: | P43353,Q53XL5, Q8N515, Q96CK8, A3FMP9, |
UniProt Related Accession: | P43353 |
Molecular Weight: | 47,683 Da |
NCBI Full Name: | Aldehyde dehydrogenase family 3 member B1 |
NCBI Synonym Full Names: | aldehyde dehydrogenase 3 family member B1 |
NCBI Official Symbol: | ALDH3B1 |
NCBI Official Synonym Symbols: | ALDH4; ALDH7 |
NCBI Protein Information: | aldehyde dehydrogenase family 3 member B1 |
UniProt Protein Name: | Aldehyde dehydrogenase family 3 member B1 |
UniProt Synonym Protein Names: | Aldehyde dehydrogenase 7 |
Protein Family: | Aldehyde dehydrogenase family |
UniProt Gene Name: | ALDH3B1 |
UniProt Entry Name: | AL3B1_HUMAN |