ALDH3A1 Antibody, Biotin conjugated (PACO24871)
- SKU:
- PACO24871
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Description
抗体名: | ALDH3A1 Antibody, Biotin conjugated (PACO24871) |
抗体コード: | PACO24871 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Aldehyde dehydrogenase, dimeric NADP-preferring protein (210-453AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. |
シノニム: | Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDHIII) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A1), ALDH3A1, ALDH3 |
UniProt Protein Function: | ALDH3A1: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. Belongs to the aldehyde dehydrogenase family. |
UniProt Protein Details: | Protein type:Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - phenylalanine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.2.1.5; Amino Acid Metabolism - histidine; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - tyrosine; Oxidoreductase Chromosomal Location of Human Ortholog: 17p11.2 Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; extracellular space; intracellular membrane-bound organelle; nucleoplasm; plasma membrane Molecular Function:3-chloroallyl aldehyde dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; benzaldehyde dehydrogenase (NAD+) activity; protein binding Biological Process: aldehyde metabolic process; xenobiotic metabolic process |
NCBI Summary: | Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] |
UniProt Code: | P30838 |
NCBI GenInfo Identifier: | 311033473 |
NCBI Gene ID: | 218 |
NCBI Accession: | P30838.3 |
UniProt Secondary Accession: | P30838,Q9BT37, A8K828, |
UniProt Related Accession: | P30838 |
Molecular Weight: | 50,395 Da |
NCBI Full Name: | Aldehyde dehydrogenase, dimeric NADP-preferring |
NCBI Synonym Full Names: | aldehyde dehydrogenase 3 family member A1 |
NCBI Official Symbol: | ALDH3A1 |
NCBI Official Synonym Symbols: | ALDH3; ALDHIII |
NCBI Protein Information: | aldehyde dehydrogenase, dimeric NADP-preferring |
UniProt Protein Name: | Aldehyde dehydrogenase, dimeric NADP-preferring |
UniProt Synonym Protein Names: | ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1 |
Protein Family: | Aldehyde dehydrogenase |
UniProt Gene Name: | ALDH3A1 |
UniProt Entry Name: | AL3A1_HUMAN |